Brain cell type-specific enhancer-promoter interactome maps and disease - risk association
Nott, Alexi, Holtman, Inge R, Coufal, Nicole G, Schlachetzki, Johannes C M, Yu, Miao, Hu, Rong, Han, Claudia Z, Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P, O'Connor, Carolyn, Nickl, Christian K, Schafer, Simon T, Shen, Zeyang, Rissman, Robert A, Brewer, James B, Gosselin, David, Gonda, David D, Levy, Michael L, Rosenfeld, Michael G, McVicker, Graham, Gage, Fred H, Ren, Bing, Glass, Christopher K
Published in Science (American Association for the Advancement of Science) (29.11.2019)
Published in Science (American Association for the Advancement of Science) (29.11.2019)
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Journal Article
Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain
Han, Jinju, Kim, Hyung Joon, Schafer, Simon T., Paquola, Apua, Clemenson, Gregory D., Toda, Tomohisa, Oh, Jinseo, Pankonin, Aimee R., Lee, Bo Suk, Johnston, Stephen T., Sarkar, Anindita, Denli, Ahmet M., Gage, Fred H.
Published in Neuron (Cambridge, Mass.) (06.07.2016)
Published in Neuron (Cambridge, Mass.) (06.07.2016)
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Journal Article
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons
Schafer, Simon T., Paquola, Apua C. M., Stern, Shani, Gosselin, David, Ku, Manching, Pena, Monique, Kuret, Thomas J. M., Liyanage, Marvin, Mansour, Abed AlFatah, Jaeger, Baptiste N., Marchetto, Maria C., Glass, Christopher K., Mertens, Jerome, Gage, Fred H.
Published in Nature neuroscience (01.02.2019)
Published in Nature neuroscience (01.02.2019)
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Journal Article
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Mertens, Jerome, Wang, Qiu-Wen, Kim, Yongsung, Yu, Diana X., Pham, Son, Yang, Bo, Zheng, Yi, Diffenderfer, Kenneth E., Zhang, Jian, Soltani, Sheila, Eames, Tameji, Schafer, Simon T., Boyer, Leah, Marchetto, Maria C., Nurnberger, John I., Calabrese, Joseph R., Oedegaard, Ketil J., McCarthy, Michael J., Zandi, Peter P., Alda, Martin, Nievergelt, Caroline M., Mi, Shuangli, Brennand, Kristen J., Kelsoe, John R., Gage, Fred H., Yao, Jun
Published in Nature (London) (05.11.2015)
Published in Nature (London) (05.11.2015)
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Journal Article
A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
Jaeger, Baptiste N., Linker, Sara B., Parylak, Sarah L., Barron, Jerika J., Gallina, Iryna S., Saavedra, Christian D., Fitzpatrick, Conor, Lim, Christina K., Schafer, Simon T., Lacar, Benjamin, Jessberger, Sebastian, Gage, Fred H.
Published in Nature communications (06.08.2018)
Published in Nature communications (06.08.2018)
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Journal Article
In vivo imaging of dendritic pruning in dentate granule cells
Gonçalves, J Tiago, Bloyd, Cooper W, Shtrahman, Matthew, Johnston, Stephen T, Schafer, Simon T, Parylak, Sarah L, Tran, Thanh, Chang, Tina, Gage, Fred H
Published in Nature neuroscience (01.06.2016)
Published in Nature neuroscience (01.06.2016)
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Journal Article
Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
Krüger, Anne, Oldenburg, Marina, Chebrolu, Chiranjeevi, Beisser, Daniela, Kolter, Julia, Sigmund, Anna M, Steinmann, Jörg, Schäfer, Simon, Hochrein, Hubertus, Rahmann, Sven, Wagner, Hermann, Henneke, Philipp, Hornung, Veit, Buer, Jan, Kirschning, Carsten J
Published in EMBO reports (01.12.2015)
Published in EMBO reports (01.12.2015)
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Journal Article
AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study
Rump, Katharina, Unterberg, Matthias, Bergmann, Lars, Bankfalvi, Agnes, Menon, Anil, Schäfer, Simon, Scherag, André, Bazzi, Zainab, Siffert, Winfried, Peters, Jürgen, Adamzik, Michael
Published in Journal of translational medicine (21.11.2016)
Published in Journal of translational medicine (21.11.2016)
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Journal Article
Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons
Herdy, Joseph, Schafer, Simon, Kim, Yongsung, Ansari, Zoya, Zangwill, Dina, Ku, Manching, Paquola, Apua, Lee, Hyungjun, Mertens, Jerome, Gage, Fred H
Published in eLife (17.05.2019)
Published in eLife (17.05.2019)
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Journal Article
Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders
Bermperidis, Theodoros, Schafer, Simon, Gage, Fred H, Sejnowski, Terrence, Torres, Elizabeth B
Published in Frontiers in neuroscience (02.06.2022)
Published in Frontiers in neuroscience (02.06.2022)
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Journal Article
A New Approach for Air Cargo Network Planning
Derigs, Ulrich, Friederichs, Stefan, Schafer, Simon
Published in Transportation science (01.08.2009)
Published in Transportation science (01.08.2009)
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Journal Article
Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells
Soni, Abhinav, Klütsch, Diana, Hu, Xin, Houtman, Judith, Rund, Nicole, McCloskey, Asako, Mertens, Jerome, Schafer, Simon T, Amin, Hayder, Toda, Tomohisa
Published in Cells (Basel, Switzerland) (26.07.2021)
Published in Cells (Basel, Switzerland) (26.07.2021)
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Journal Article
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
Stern, Shani, Lau, Shong, Manole, Andreea, Rosh, Idan, Percia, Menachem Mendel, Ben Ezer, Ran, Shokhirev, Maxim N., Qiu, Fan, Schafer, Simon, Mansour, Abed AlFatah, Mangan, Kile P., Stern, Tchelet, Ofer, Polina, Stern, Yam, Diniz Mendes, Ana Paula, Djamus, Jose, Moore, Lynne Randolph, Nayak, Ritu, Laufer, Sapir Havusha, Aicher, Aidan, Rhee, Amanda, Wong, Thomas L., Nguyen, Thao, Linker, Sara B., Winner, Beate, Freitas, Beatriz C., Jones, Eugenia, Sagi, Irit, Bardy, Cedric, Brice, Alexis, Winkler, Juergen, Marchetto, Maria C., Gage, Fred H.
Published in NPJ Parkinson's Disease (10.08.2022)
Published in NPJ Parkinson's Disease (10.08.2022)
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Journal Article
Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Mertens, Jerome, Wang, Qiu-Wen, Kim, Yongsung, Yu, Diana X., Pham, Son, Yang, Bo, Zheng, Yi, Diffenderfer, Kenneth E., Zhang, Jian, Soltani, Sheila, Eames, Tameji, Schafer, Simon T., Boyer, Leah, Marchetto, Maria C., Nurnberger, John I., Calabrese, Joseph R., Oedegaard, Ketil J., McCarthy, Michael J., Zandi, Peter P., Alda, Martin, Nievergelt, Caroline M., Mi, Shuangli, Brennand, Kristen J., Kelsoe, John R., Gage, Fred H., Yao, Jun
Published in Nature (London) (11.02.2016)
Published in Nature (London) (11.02.2016)
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Journal Article
Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock
Schäfer, Simon T, Gessner, Sophia, Scherag, André, Rump, Katharina, Frey, Ulrich H, Siffert, Winfried, Westendorf, Astrid M, Steinmann, Jörg, Peters, Jürgen, Adamzik, Michael
Published in PloS one (18.08.2014)
Published in PloS one (18.08.2014)
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Journal Article
Physiological mechanisms behind respiratory variations in right atrial pressure in pulmonary hypertension
Yogeswaran, Athiththan, da Rocha, Bruno Brito, Rako, Zvonimir A., Kaufmann, Samuel J., Schäfer, Simon, Kremer, Nils, Ghofrani, Hossein Ardeschir, Seeger, Werner, Tello, Khodr
Published in Scientific reports (31.05.2024)
Published in Scientific reports (31.05.2024)
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Journal Article
DNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsis
Rump, Katharina, Unterberg, Matthias, Dahlke, Agnes, Nowak, Hartmuth, Koos, Björn, Bergmann, Lars, Siffert, Winfried, Schäfer, Simon T., Peters, Jürgen, Adamzik, Michael, Rahmel, Tim
Published in Scientific reports (06.12.2019)
Published in Scientific reports (06.12.2019)
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Journal Article
Functional testing of tranexamic acid effects in patients undergoing elective orthopaedic surgery
Groene, Philipp, Sappel, Sophia R., Saller, Thomas, Nitschke, Tobias, Sa, Paula A., Paulus, Alexander, Chappell, Daniel, Schäfer, Simon T.
Published in Journal of thrombosis and thrombolysis (01.05.2021)
Published in Journal of thrombosis and thrombolysis (01.05.2021)
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