Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity
Murphy, Anna, Cwiklinski, Krystyna, Lalor, Richard, O'Connell, Barry, Robinson, Mark W, Gerlach, Jared, Joshi, Lokesh, Kilcoyne, Michelle, Dalton, John P, O'Neill, Sandra M
Published in PLoS neglected tropical diseases (01.09.2020)
Published in PLoS neglected tropical diseases (01.09.2020)
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Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells
de la Torre-Escudero, Eduardo, Gerlach, Jared Q, Bennett, Adam P S, Cwiklinski, Krystyna, Jewhurst, Heather L, Huson, Kathryn M, Joshi, Lokesh, Kilcoyne, Michelle, O'Neill, Sandra, Dalton, John P, Robinson, Mark W
Published in PLoS neglected tropical diseases (01.01.2019)
Published in PLoS neglected tropical diseases (01.01.2019)
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Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
Cwiklinski, Krystyna, Robinson, Mark W, Donnelly, Sheila, Dalton, John P
Published in BMC genomics (11.01.2021)
Published in BMC genomics (11.01.2021)
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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins
De Marco Verissimo, Carolina, Jewhurst, Heather L, Dobó, József, Gál, Péter, Dalton, John P, Cwiklinski, Krystyna
Published in PLoS pathogens (01.01.2022)
Published in PLoS pathogens (01.01.2022)
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Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases
De Marco Verissimo, Carolina, Jewhurst, Heather L, Tikhonova, Irina G, Urbanus, Rolf T, Maule, Aaron G, Dalton, John P, Cwiklinski, Krystyna
Published in PLoS neglected tropical diseases (01.08.2020)
Published in PLoS neglected tropical diseases (01.08.2020)
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Fasciola hepatica -Derived Molecules as Regulators of the Host Immune Response
Ryan, Sinéad, Shiels, Jenna, Taggart, Clifford C, Dalton, John P, Weldon, Sinéad
Published in Frontiers in immunology (02.09.2020)
Published in Frontiers in immunology (02.09.2020)
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A new multiplex SARS-CoV-2 antigen microarray showed correlation of IgG, IgA, and IgM antibodies from patients with COVID-19 disease severity and maintenance of relative IgA and IgM antigen binding over time
Berre, Marie Le, Paulovčáková, Terézia, Verissimo, Carolina De Marco, Doyle, Seán, Dalton, John P, Masterson, Claire, Martínez, Eduardo Ribes, Walsh, Laura, Gormley, Conor, Laffey, John G, McNicholas, Bairbre, Simpkin, Andrew J, Kilcoyne, Michelle
Published in PloS one (30.03.2023)
Published in PloS one (30.03.2023)
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Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica
Ricafrente, Alison, Cwiklinski, Krystyna, Nguyen, Hieu, Dalton, John P, Tran, Nham, Donnelly, Sheila
Published in BMC genomics (04.06.2022)
Published in BMC genomics (04.06.2022)
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Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host
Cwiklinski, Krystyna, Jewhurst, Heather, McVeigh, Paul, Barbour, Tara, Maule, Aaron G., Tort, Jose, O'Neill, Sandra M., Robinson, Mark W., Donnelly, Sheila, Dalton, John P.
Published in Molecular & cellular proteomics (01.04.2018)
Published in Molecular & cellular proteomics (01.04.2018)
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The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis [S]
Cwiklinski, Krystyna, de la Torre-Escudero, Eduardo, Trelis, Maria, Bernal, Dolores, Dufresne, PhilippeJ, Brennan, GerardP, O'Neill, Sandra, Tort, Jose, Paterson, Steve, Marcilla, Antonio, Dalton, JohnP, Robinson, MarkW
Published in Molecular & cellular proteomics (01.12.2015)
Published in Molecular & cellular proteomics (01.12.2015)
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Exploring the utility of circulating miRNAs as diagnostic biomarkers of fasciolosis
Chowdhury, Sumaiya, Ricafrente, Alison, Cwiklinski, Krystyna, Sais, Dayna, Dalton, John P., Tran, Nham, Donnelly, Sheila
Published in Scientific reports (28.03.2024)
Published in Scientific reports (28.03.2024)
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Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase
Tallima, Hatem, Dvořák, Jan, Kareem, Sahira, Abou El Dahab, Marwa, Abdel Aziz, Nada, Dalton, John Pius, El Ridi, Rashika
Published in PLoS neglected tropical diseases (27.03.2017)
Published in PLoS neglected tropical diseases (27.03.2017)
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Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses
Tran, Nham, Ricafrente, Alison, To, Joyce, Lund, Maria, Marques, Tania M., Gama-Carvalho, Margarida, Cwiklinski, Krystyna, Dalton, John P., Donnelly, Sheila
Published in Scientific reports (24.03.2021)
Published in Scientific reports (24.03.2021)
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An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host
Robinson, Mark W, Menon, Ranjeeta, Donnelly, Sheila M, Dalton, John P, Ranganathan, Shoba
Published in Molecular & cellular proteomics (01.08.2009)
Published in Molecular & cellular proteomics (01.08.2009)
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Cysteine peptidases as schistosomiasis vaccines with inbuilt adjuvanticity
El Ridi, Rashika, Tallima, Hatem, Selim, Sahar, Donnelly, Sheila, Cotton, Sophie, Gonzales Santana, Bibiana, Dalton, John P
Published in PloS one (21.01.2014)
Published in PloS one (21.01.2014)
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Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouse
Lund, Maria E, O'Brien, Bronwyn A, Hutchinson, Andrew T, Robinson, Mark W, Simpson, Ann M, Dalton, John P, Donnelly, Sheila
Published in PloS one (21.01.2014)
Published in PloS one (21.01.2014)
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A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides
Robinson, Mark W, Donnelly, Sheila, Hutchinson, Andrew T, To, Joyce, Taylor, Nicole L, Norton, Raymond S, Perugini, Matthew A, Dalton, John P
Published in PLoS pathogens (01.05.2011)
Published in PLoS pathogens (01.05.2011)
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The diagnosis of human fascioliasis by enzyme-linked immunosorbent assay (ELISA) using recombinant cathepsin L protease
Gonzales Santana, Bibiana, Dalton, John P, Vasquez Camargo, Fabio, Parkinson, Michael, Ndao, Momar
Published in PLoS neglected tropical diseases (01.09.2013)
Published in PLoS neglected tropical diseases (01.09.2013)
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