Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy
West, Anthony P., Scharf, Louise, Scheid, Johannes F., Klein, Florian, Bjorkman, Pamela J., Nussenzweig, Michel C.
Published in Cell (13.02.2014)
Published in Cell (13.02.2014)
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Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
Mouquet, Hugo, Scharf, Louise, Euler, Zelda, Liu, Yan, Eden, Caroline, Scheid, Johannes F., Halper-Stromberg, Ariel, Gnanapragasam, Priyanthi N. P., Spencer, Daniel I. R., Seaman, Michael S., Schuitemaker, Hanneke, Feizi, Ten, Nussenzweig, Michel C., Bjorkman, Pamela J.
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2012)
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Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
Dosenovic, Pia, von Boehmer, Lotta, Escolano, Amelia, Jardine, Joseph, Freund, Natalia T., Gitlin, Alexander D., McGuire, Andrew T., Kulp, Daniel W., Oliveira, Thiago, Scharf, Louise, Pietzsch, John, Gray, Matthew D., Cupo, Albert, van Gils, Marit J., Yao, Kai-Hui, Liu, Cassie, Gazumyan, Anna, Seaman, Michael S., Björkman, Pamela J., Sanders, Rogier W., Moore, John P., Stamatatos, Leonidas, Schief, William R., Nussenzweig, Michel C.
Published in Cell (18.06.2015)
Published in Cell (18.06.2015)
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Journal Article
Computational analysis of anti–HIV-1 antibody neutralization panel data to identify potential functional epitope residues
West, Anthony P., Scharf, Louise, Horwitz, Joshua, Klein, Florian, Nussenzweig, Michel C., Bjorkman, Pamela J.
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.2013)
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Journal Article
Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike
Scharf, Louise, Scheid, Johannes F., Lee, Jeong Hyun, West, Anthony P., Chen, Courtney, Gao, Han, Gnanapragasam, Priyanthi N.P., Mares, René, Seaman, Michael S., Ward, Andrew B., Nussenzweig, Michel C., Bjorkman, Pamela J.
Published in Cell reports (Cambridge) (01.05.2014)
Published in Cell reports (Cambridge) (01.05.2014)
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A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies
Ding, Shilei, Veillette, Maxime, Coutu, Mathieu, Prévost, Jérémie, Scharf, Louise, Bjorkman, Pamela J, Ferrari, Guido, Robinson, James E, Stürzel, Christina, Hahn, Beatrice H, Sauter, Daniel, Kirchhoff, Frank, Lewis, George K, Pazgier, Marzena, Finzi, Andrés
Published in Journal of virology (15.02.2016)
Published in Journal of virology (15.02.2016)
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Recognition of lyso-phospholipids by human natural killer T lymphocytes
Fox, Lisa M, Cox, Daryl G, Lockridge, Jennifer L, Wang, Xiaohua, Chen, Xiuxu, Scharf, Louise, Trott, David L, Ndonye, Rachel M, Veerapen, Natacha, Besra, Gurdyal S, Howell, Amy R, Cook, Mark E, Adams, Erin J, Hildebrand, William H, Gumperz, Jenny E
Published in PLoS biology (01.10.2009)
Published in PLoS biology (01.10.2009)
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Journal Article
Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody
Scharf, Louise, West, Anthony P., Gao, Han, Lee, Terri, Scheid, Johannes F., Nussenzweig, Michel C., Bjorkman, Pamela J., Diskin, Ron
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
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Journal Article
Structural basis for germline antibody recognition of HIV-1 immunogens
Scharf, Louise, West, Anthony P, Sievers, Stuart A, Chen, Courtney, Jiang, Siduo, Gao, Han, Gray, Matthew D, McGuire, Andrew T, Scheid, Johannes F, Nussenzweig, Michel C, Stamatatos, Leonidas, Bjorkman, Pamela J
Published in eLife (21.03.2016)
Published in eLife (21.03.2016)
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Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice
Chiuppesi, Flavia, Wussow, Felix, Scharf, Louise, Contreras, Heidi, Gao, Han, Meng, Zhuo, Nguyen, Jenny, Barry, Peter A, Bjorkman, Pamela J, Diamond, Don J
Published in PloS one (16.08.2017)
Published in PloS one (16.08.2017)
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Journal Article
Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies
Wang, Haoqing, Gristick, Harry B, Scharf, Louise, West, Anthony P, Galimidi, Rachel P, Seaman, Michael S, Freund, Natalia T, Nussenzweig, Michel C, Bjorkman, Pamela J
Published in eLife (26.05.2017)
Published in eLife (26.05.2017)
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A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo
Freund, Natalia T, Horwitz, Joshua A, Nogueira, Lilian, Sievers, Stuart A, Scharf, Louise, Scheid, Johannes F, Gazumyan, Anna, Liu, Cassie, Velinzon, Klara, Goldenthal, Ariel, Sanders, Rogier W, Moore, John P, Bjorkman, Pamela J, Seaman, Michael S, Walker, Bruce D, Klein, Florian, Nussenzweig, Michel C
Published in PLoS pathogens (01.10.2015)
Published in PLoS pathogens (01.10.2015)
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Journal Article
Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env
Scharf, Louise, Wang, Haoqing, Gao, Han, Chen, Songye, McDowall, Alasdair W., Bjorkman, Pamela J.
Published in Cell (10.09.2015)
Published in Cell (10.09.2015)
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Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells
Luoma, Adrienne M., Castro, Caitlin D., Mayassi, Toufic, Bembinster, Leslie A., Bai, Li, Picard, Damien, Anderson, Brian, Scharf, Louise, Kung, Jennifer E., Sibener, Leah V., Savage, Paul B., Jabri, Bana, Bendelac, Albert, Adams, Erin J.
Published in Immunity (Cambridge, Mass.) (12.12.2013)
Published in Immunity (Cambridge, Mass.) (12.12.2013)
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Journal Article
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
Freund, Natalia T, Wang, Haoqing, Scharf, Louise, Nogueira, Lilian, Horwitz, Joshua A, Bar-On, Yotam, Golijanin, Jovana, Sievers, Stuart A, Sok, Devin, Cai, Hui, Cesar Lorenzi, Julio C, Halper-Stromberg, Ariel, Toth, Ildiko, Piechocka-Trocha, Alicja, Gristick, Harry B, van Gils, Marit J, Sanders, Rogier W, Wang, Lai-Xi, Seaman, Michael S, Burton, Dennis R, Gazumyan, Anna, Walker, Bruce D, West, Jr, Anthony P, Bjorkman, Pamela J, Nussenzweig, Michel C
Published in Science translational medicine (18.01.2017)
Published in Science translational medicine (18.01.2017)
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Antibody engineering for increased potency, breadth and half-life
Sievers, Stuart A, Scharf, Louise, West, Jr, Anthony P, Bjorkman, Pamela J
Published in Current opinion in HIV & AIDS (01.05.2015)
Published in Current opinion in HIV & AIDS (01.05.2015)
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Journal Article
The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation
Scharf, Louise, Li, Nan-Sheng, Hawk, Andrew J., Garzón, Diana, Zhang, Tejia, Fox, Lisa M., Kazen, Allison R., Shah, Sneha, Haddadian, Esmael J., Gumperz, Jenny E., Saghatelian, Alan, Faraldo-Gómez, José D., Meredith, Stephen C., Piccirilli, Joseph A., Adams, Erin J.
Published in Immunity (Cambridge, Mass.) (14.12.2010)
Published in Immunity (Cambridge, Mass.) (14.12.2010)
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Journal Article
γδ T Cell Receptors Recognize the Non-classical Major Histocompatibility Complex (MHC) Molecule T22 via Conserved Anchor Residues in a MHC Peptide-like Fashion
Sandstrom, Andrew, Scharf, Louise, McRae, Gabrielle, Hawk, Andrew J., Meredith, Stephen C., Adams, Erin J.
Published in The Journal of biological chemistry (17.02.2012)
Published in The Journal of biological chemistry (17.02.2012)
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