Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands
de Medina, Philippe, Paillasse, Michael R., Ségala, Gregory, Khallouki, Farid, Brillouet, Severine, Dalenc, Florence, Courbon, Frederic, Record, Michel, Poirot, Marc, Silvente-Poirot, Sandrine
Published in Chemistry and physics of lipids (01.09.2011)
Published in Chemistry and physics of lipids (01.09.2011)
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Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands
de Medina, Philippe, Paillasse, Michael R., Segala, Gregory, Poirot, Marc, Silvente-Poirot, Sandrine, Mangelsdorf, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (27.07.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (27.07.2010)
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Journal Article
Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers
Segala, Gregory, Bennesch, Marcela A., Pandey, Deo Prakash, Hulo, Nicolas, Picard, Didier
Published in Molecular cell (20.10.2016)
Published in Molecular cell (20.10.2016)
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Journal Article
Ligand-dependent transcriptional induction of lethal autophagy: A new perspective for cancer treatment
Silvente-Poirot, Sandrine, Segala, Gregory, Poirot, Mathias C., Poirot, Marc
Published in Autophagy (04.03.2018)
Published in Autophagy (04.03.2018)
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Journal Article
Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
Segala, Gregory, Bennesch, Marcela A., Ghahhari, Nastaran Mohammadi, Pandey, Deo Prakash, Echeverria, Pablo C., Karch, François, Maeda, Robert K., Picard, Didier
Published in Nature communications (23.04.2019)
Published in Nature communications (23.04.2019)
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Journal Article
5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of Tamoxifen in breast cancer cells
Segala, Gregory, de Medina, Philippe, Iuliano, Luigi, Zerbinati, Chiara, Paillasse, Michael R., Noguer, Emmanuel, Dalenc, Florence, Payré, Bruno, Jordan, V. Craig, Record, Michel, Silvente-Poirot, Sandrine, Poirot, Marc
Published in Biochemical pharmacology (01.07.2013)
Published in Biochemical pharmacology (01.07.2013)
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Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor
Voisin, Maud, de Medina, Philippe, Mallinger, Arnaud, Dalenc, Florence, Huc-Claustre, Emilie, Leignadier, Julie, Serhan, Nizar, Soules, Régis, Ségala, Grégory, Mougel, Aurélie, Noguer, Emmanuel, Mhamdi, Loubna, Bacquié, Elodie, Iuliano, Luigi, Zerbinati, Chiara, Lacroix-Triki, Magali, Chaltiel, Léonor, Filleron, Thomas, Cavaillès, Vincent, Saati, Talal Al, Rochaix, Philippe, Duprez-Paumier, Raphaelle, Franchet, Camille, Ligat, Laetitia, Lopez, Fréderic, Record, Michel, Poirot, Marc, Silvente-Poirot, Sandrine
Published in Proceedings of the National Academy of Sciences - PNAS (31.10.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (31.10.2017)
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LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP
Bennesch, Marcela A, Segala, Gregory, Wider, Diana, Picard, Didier
Published in Nucleic acids research (14.10.2016)
Published in Nucleic acids research (14.10.2016)
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Journal Article
Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties
de Medina, Philippe, Paillasse, Michael R., Segala, Gregory, Voisin, Maud, Mhamdi, Loubna, Dalenc, Florence, Lacroix-Triki, Magali, Filleron, Thomas, Pont, Frederic, Saati, Talal Al, Morisseau, Christophe, Hammock, Bruce D., Silvente-Poirot, Sandrine, Poirot, Marc
Published in Nature communications (2013)
Published in Nature communications (2013)
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Journal Article
Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A
de Medina, Philippe, Paillasse, Michael R., Segala, Gregory, Al Saati, Talal, Boyes, Jeannine, Delsol, Georges, Allal, Cuider, Marsili, Sabrina, Silvente-Poirot, Sandrine, Poirot, Marc
Published in Biochimie (01.03.2013)
Published in Biochimie (01.03.2013)
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