Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439)
Kim, Ho Shin, Hammill, Jared T, Guy, R. Kiplin
Published in Journal of medicinal chemistry (13.04.2017)
Published in Journal of medicinal chemistry (13.04.2017)
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Journal Article
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M
Kim, Ho Shin, Hammill, Jared T., Scott, Daniel C., Chen, Yizhe, Rice, Amy L., Pistel, William, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Journal Article
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase
Scott, Daniel C, Hammill, Jared T, Min, Jaeki, Rhee, David Y, Connelly, Michele, Sviderskiy, Vladislav O, Bhasin, Deepak, Chen, Yizhe, Ong, Su-Sien, Chai, Sergio C, Goktug, Asli N, Huang, Guochang, Monda, Julie K, Low, Jonathan, Kim, Ho Shin, Paulo, Joao A, Cannon, Joe R, Shelat, Anang A, Chen, Taosheng, Kelsall, Ian R, Alpi, Arno F, Pagala, Vishwajeeth, Wang, Xusheng, Peng, Junmin, Singh, Bhuvanesh, Harper, J Wade, Schulman, Brenda A, Guy, R Kip
Published in Nature chemical biology (01.08.2017)
Published in Nature chemical biology (01.08.2017)
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Journal Article
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides
Kim, Ho Shin, Ortiz, Diana, Kadayat, Tara Man, Fargo, Corinne M., Hammill, Jared T., Chen, Yizhe, Rice, Amy L., Begley, Kristin L., Shoeran, Gaurav, Pistel, William, Yates, Phillip A., Sanchez, Marco A., Landfear, Scott M., Guy, R. Kiplin
Published in Journal of medicinal chemistry (08.06.2023)
Published in Journal of medicinal chemistry (08.06.2023)
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Journal Article
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents
Hammill, Jared T., Sviripa, Vitaliy M., Kril, Liliia M., Ortiz, Diana, Fargo, Corinne M., Kim, Ho Shin, Chen, Yizhe, Rector, Jonah, Rice, Amy L., Domagalska, Malgorzata A., Begley, Kristin L., Liu, Chunming, Rangnekar, Vivek M., Dujardin, Jean-Claude, Watt, David S., Landfear, Scott M., Guy, R. Kiplin
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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Journal Article
Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4‑b]pyridines
Eagon, Scott, Hammill, Jared T, Sigal, Martina, Ahn, Kevin J, Tryhorn, Julia E, Koch, Grant, Belanger, Briana, Chaplan, Cory A, Loop, Lauren, Kashtanova, Anna S, Yniguez, Kenya, Lazaro, Horacio, Wilkinson, Steven P, Rice, Amy L, Falade, Mofolusho O, Takahashi, Rei, Kim, Katie, Cheung, Ashley, DiBernardo, Celine, Kimball, Joshua J, Winzeler, Elizabeth A, Eribez, Korina, Mittal, Nimisha, Gamo, Francisco-Javier, Crespo, Benigno, Churchyard, Alisje, García-Barbazán, Irene, Baum, Jake, Anderson, Marc O, Laleu, Benoît, Guy, R. Kiplin
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Journal Article
Antimalarial activity of 2,6-dibenzylidenecyclohexanone derivatives
Eagon, Scott, Hammill, Jared T., Fitzsimmons, Kasey, Sienko, Natalie, Nguyen, Brandon, Law, Jarvis, Manjunath, Aashrita, Wilkinson, Steven P., Thompson, Kara, Glidden, Julia Elizabeth, Rice, Amy L., Falade, Mofolusho O., Kimball, Joshua J., DiBernardo, Celine, Guy, R. Kiplin
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
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Journal Article
Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening
Ortiz, Diana, Guiguemde, W Armand, Hammill, Jared T, Carrillo, Angela K, Chen, Yizhe, Connelly, Michele, Stalheim, Kayla, Elya, Carolyn, Johnson, Alex, Min, Jaeki, Shelat, Anang, Smithson, David C, Yang, Lei, Zhu, Fangyi, Guy, R Kiplin, Landfear, Scott M
Published in PLoS neglected tropical diseases (01.12.2017)
Published in PLoS neglected tropical diseases (01.12.2017)
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Journal Article
Probing Protein Folding Using Site-Specifically Encoded Unnatural Amino Acids as FRET Donors with Tryptophan
Miyake-Stoner, Shigeki J, Miller, Andrew M, Hammill, Jared T, Peeler, Jennifer C, Hess, Kenneth R, Mehl, Ryan A, Brewer, Scott H
Published in Biochemistry (Easton) (30.06.2009)
Published in Biochemistry (Easton) (30.06.2009)
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Journal Article
Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development
Gaur, Aditya H., Panetta, John C., Smith, Amber M., Dallas, Ronald H., Freeman, Burgess B., Stewart, Tracy B., Tang, Li, John, Elizabeth, Branum, Kristen C., Patel, Nehali D., Ost, Shelley, Heine, Ryan N., Richardson, Julie L., Hammill, Jared T., Bebrevska, Lidiya, Gusovsky, Fabian, Maki, Noritsugu, Yanagi, Toshiharu, Flynn, Patricia M., McCarthy, James S., Chalon, Stephan, Guy, R. Kiplin
Published in EBioMedicine (01.06.2022)
Published in EBioMedicine (01.06.2022)
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Journal Article
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A
Zuniga, Jorge E, Hammill, Jared T, Drory, Omri, Nuss, Jonathan E, Burnett, James C, Gussio, Rick, Wipf, Peter, Bavari, Sina, Brunger, Axel T
Published in PloS one (30.06.2010)
Published in PloS one (30.06.2010)
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Journal Article