Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release
Samstad, Eivind O, Niyonzima, Nathalie, Nymo, Stig, Aune, Marie H, Ryan, Liv, Bakke, Siril S, Lappegård, Knut T, Brekke, Ole-Lars, Lambris, John D, Damås, Jan K, Latz, Eicke, Mollnes, Tom E, Espevik, Terje
Published in The Journal of immunology (1950) (15.03.2014)
Published in The Journal of immunology (1950) (15.03.2014)
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Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
Gravastrand, Caroline S, Steinkjer, Bjørg, Halvorsen, Bente, Landsem, Anne, Skjelland, Mona, Jacobsen, Eva Astrid, Woodruff, Trent M, Lambris, John D, Mollnes, Tom E, Brekke, Ole-Lars, Espevik, Terje, Rokstad, Anne Mari A
Published in The Journal of immunology (1950) (15.08.2019)
Published in The Journal of immunology (1950) (15.08.2019)
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Complement C3b contributes to Escherichia coli -induced platelet aggregation in human whole blood
Landsem, Anne, Emblem, Åse, Lau, Corinna, Christiansen, Dorte, Gerogianni, Alexandra, Karlsen, Bård Ove, Mollnes, Tom Eirik, Nilsson, Per H, Brekke, Ole-Lars
Published in Frontiers in immunology (14.12.2022)
Published in Frontiers in immunology (14.12.2022)
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A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
Nielsen, Erik Waage, Miller, Yoav, Brekke, Ole-Lars, Grond, Joost, Duong, Anh Hoang, Fure, Hilde, Ludviksen, Judith Krey, Pettersen, Kristin, Reubsaet, Leon, Solberg, Rigmor, Johansen, Harald Thidemann, Mollnes, Tom Eirik
Published in Frontiers in immunology (01.04.2022)
Published in Frontiers in immunology (01.04.2022)
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Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism
Høiland, Ina Isabella, Liang, Robin Amanda, Hindberg, Kristian, Latysheva, Nadezhda, Brekke, Ole-Lars, Mollnes, Tom Eirik, Hansen, John-Bjarne
Published in Thrombosis research (01.09.2018)
Published in Thrombosis research (01.09.2018)
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Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis
Skjeflo, Espen W, Sagatun, Caroline, Dybwik, Knut, Aam, Sturla, Urving, Sven H, Nunn, Miles A, Fure, Hilde, Lau, Corinna, Brekke, Ole-Lars, Huber-Lang, Markus, Espevik, Terje, Barratt-Due, Andreas, Nielsen, Erik W, Mollnes, Tom E
Published in Critical care (London, England) (27.11.2015)
Published in Critical care (London, England) (27.11.2015)
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The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood
Brekke, Ole‐Lars, Christiansen, Dorte, Fure, Hilde, Fung, Michael, Mollnes, Tom E.
Published in Journal of leukocyte biology (01.06.2007)
Published in Journal of leukocyte biology (01.06.2007)
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CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
Lau, Corinna, Nygård, Ståle, Fure, Hilde, Olstad, Ole Kristoffer, Holden, Marit, Lappegård, Knut Tore, Brekke, Ole-Lars, Espevik, Terje, Hovig, Eivind, Mollnes, Tom Eirik
Published in PloS one (23.02.2015)
Published in PloS one (23.02.2015)
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Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood
Brekke, Ole-Lars, Christiansen, Dorte, Fure, Hilde, Pharo, Anne, Fung, Michael, Riesenfeld, Johan, Mollnes, Tom Eirik
Published in Molecular immunology (01.08.2008)
Published in Molecular immunology (01.08.2008)
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Effects on muscle strength, maximal jump height, flexibility and postural sway after soccer and Zumba exercise among female hospital employees: a 9-month randomised controlled trial
Barene, Svein, Holtermann, Andreas, Oseland, Harald, Brekke, Ole-Lars, Krustrup, Peter
Published in Journal of sports sciences (01.10.2016)
Published in Journal of sports sciences (01.10.2016)
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A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity
Nilsson, Per H, Johnson, Christina, Quach, Quang Huy, Macpherson, Alex, Durrant, Oliver, Pischke, Soeren E, Fure, Hilde, Landsem, Anne, Bergseth, Grethe, Schjalm, Camilla, Haugaard-Kedström, Linda M, Huber-Lang, Markus, van den Elsen, Jean, Brekke, Ole-Lars, Mollnes, Tom Eirik
Published in The Journal of immunology (1950) (15.09.2021)
Published in The Journal of immunology (1950) (15.09.2021)
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Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn
Hallstensen, Randi Fykse, Bergseth, Grethe, Foss, Stian, Jæger, Steinar, Gedde-Dahl, Tobias, Holt, Jan, Christiansen, Dorte, Lau, Corinna, Brekke, Ole-Lars, Armstrong, Elina, Stefanovic, Vedran, Andersen, Jan Terje, Sandlie, Inger, Mollnes, Tom Eirik
Published in Immunobiology (1979) (01.04.2015)
Published in Immunobiology (1979) (01.04.2015)
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No evidence of impaired endothelial function or altered inflammatory state in patients with familial hypercholesterolemia treated with statins
Hovland, Anders, MD, Aagnes, Inger, MD, Brekke, Ole-Lars, MD, PhD, Flage, John Helge, RN, Lappegård, Knut Tore, MD, PhD
Published in Journal of clinical lipidology (01.07.2010)
Published in Journal of clinical lipidology (01.07.2010)
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Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients
Soloey-Nilsen, Hedda, Nygaard-Odeh, Kristin, Kristiansen, Magnhild Gangsoey, Brekke, Ole Lars, Mollnes, Tom Eirik, Reitan, Solveig Klaebo, Oiesvold, Terje
Published in BMC psychiatry (03.02.2022)
Published in BMC psychiatry (03.02.2022)
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Journal Article
Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII
Gravastrand, Caroline, Hamad, Shamal, Fure, Hilde, Steinkjer, Bjørg, Ryan, Liv, Oberholzer, Josè, Lambris, John D., Lacík, Igor, Mollnes, Tom Eirik, Espevik, Terje, Brekke, Ole-Lars, Rokstad, Anne Mari
Published in Acta biomaterialia (01.08.2017)
Published in Acta biomaterialia (01.08.2017)
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Journal Article
Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model
Rokstad, Anne Mari, Brekke, Ole-Lars, Steinkjer, Bjørg, Ryan, Liv, Kolláriková, Gabriela, Strand, Berit L., Skjåk-Bræk, Gudmund, Lacík, Igor, Espevik, Terje, Mollnes, Tom Eirik
Published in Acta biomaterialia (01.06.2011)
Published in Acta biomaterialia (01.06.2011)
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Journal Article
Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood
Brekke, Ole-Lars, Christiansen, Dorte, Kisserli, Aymric, Fure, Hilde, Dahl, Jim Andre, Donvito, Béatrice, Reveil, Brigitte, Ludviksen, Judith Krey, Tabary, Thierry, Mollnes, Tom Eirik, Cohen, Jacques H.M.
Published in Molecular immunology (01.10.2019)
Published in Molecular immunology (01.10.2019)
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Journal Article
Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation
Ørning, Pontus, Hoem, Kine Samset, Coron, Abba Elizabeth, Skjåk-Bræk, Gudmund, Mollnes, Tom Eirik, Brekke, Ole-Lars, Espevik, Terje, Rokstad, Anne Mari
Published in Journal of controlled release (10.05.2016)
Published in Journal of controlled release (10.05.2016)
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