Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation
Kim, Ho Shin, Hammill, Jared T, Scott, Daniel C, Chen, Yizhe, Min, Jaeki, Rector, Jonah, Singh, Bhuvanesh, Schulman, Brenda A, Guy, R. Kiplin
Published in Journal of medicinal chemistry (26.09.2019)
Published in Journal of medicinal chemistry (26.09.2019)
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Journal Article
Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation
Hammill, Jared T, Bhasin, Deepak, Scott, Daniel C, Min, Jaeki, Chen, Yizhe, Lu, Yan, Yang, Lei, Kim, Ho Shin, Connelly, Michele C, Hammill, Courtney, Holbrook, Gloria, Jeffries, Cynthia, Singh, Bhuvanesh, Schulman, Brenda A, Guy, R. Kiplin
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M
Kim, Ho Shin, Hammill, Jared T., Scott, Daniel C., Chen, Yizhe, Rice, Amy L., Pistel, William, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Journal Article
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides
Kim, Ho Shin, Ortiz, Diana, Kadayat, Tara Man, Fargo, Corinne M., Hammill, Jared T., Chen, Yizhe, Rice, Amy L., Begley, Kristin L., Shoeran, Gaurav, Pistel, William, Yates, Phillip A., Sanchez, Marco A., Landfear, Scott M., Guy, R. Kiplin
Published in Journal of medicinal chemistry (08.06.2023)
Published in Journal of medicinal chemistry (08.06.2023)
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Journal Article
Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation
Hammill, Jared T, Scott, Daniel C, Min, Jaeki, Connelly, Michele C, Holbrook, Gloria, Zhu, Fangyi, Matheny, Amy, Yang, Lei, Singh, Bhuvanesh, Schulman, Brenda A, Guy, R. Kiplin
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents
Hammill, Jared T., Sviripa, Vitaliy M., Kril, Liliia M., Ortiz, Diana, Fargo, Corinne M., Kim, Ho Shin, Chen, Yizhe, Rector, Jonah, Rice, Amy L., Domagalska, Malgorzata A., Begley, Kristin L., Liu, Chunming, Rangnekar, Vivek M., Dujardin, Jean-Claude, Watt, David S., Landfear, Scott M., Guy, R. Kiplin
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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Journal Article
Antimalarial activity of tetrahydro-β-carbolines targeting the ATP binding pocket of the Plasmodium falciparum heat shock 90 protein
Eagon, Scott, Hammill, Jared T., Bach, Jordan, Everson, Nikalet, Sisley, Tyler A., Walls, Michael J., Durham, Sierra, Pillai, Dylan R., Falade, Mofolusho O., Rice, Amy L., Kimball, Joshua J., Lazaro, Horacio, DiBernardo, Celine, Kiplin Guy, R.
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
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Journal Article
Evaluation of 1,1-cyclopropylidene as a thioether isostere in the 4-thio-thienopyrimidine (TTP) series of antimalarials
Barrows, Robert D., Hammill, Jared T., Tran, Michael C., Falade, Mofolusho O., Rice, Amy L., Davis, Christopher W., Emge, Thomas J., Rablen, Paul R., Kiplin Guy, R., Knapp, Spencer
Published in Bioorganic & medicinal chemistry (15.11.2020)
Published in Bioorganic & medicinal chemistry (15.11.2020)
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Journal Article
Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4‑b]pyridines
Eagon, Scott, Hammill, Jared T, Sigal, Martina, Ahn, Kevin J, Tryhorn, Julia E, Koch, Grant, Belanger, Briana, Chaplan, Cory A, Loop, Lauren, Kashtanova, Anna S, Yniguez, Kenya, Lazaro, Horacio, Wilkinson, Steven P, Rice, Amy L, Falade, Mofolusho O, Takahashi, Rei, Kim, Katie, Cheung, Ashley, DiBernardo, Celine, Kimball, Joshua J, Winzeler, Elizabeth A, Eribez, Korina, Mittal, Nimisha, Gamo, Francisco-Javier, Crespo, Benigno, Churchyard, Alisje, García-Barbazán, Irene, Baum, Jake, Anderson, Marc O, Laleu, Benoît, Guy, R. Kiplin
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Journal Article
Antimalarial activity of 2,6-dibenzylidenecyclohexanone derivatives
Eagon, Scott, Hammill, Jared T., Fitzsimmons, Kasey, Sienko, Natalie, Nguyen, Brandon, Law, Jarvis, Manjunath, Aashrita, Wilkinson, Steven P., Thompson, Kara, Glidden, Julia Elizabeth, Rice, Amy L., Falade, Mofolusho O., Kimball, Joshua J., DiBernardo, Celine, Guy, R. Kiplin
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
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Journal Article
Synthesis and chemical diversity analysis of bicyclo[3.3.1]non-3-en-2-ones
Hammill, Jared T., Contreras-García, Julia, Virshup, Aaron M., Beratan, David N., Yang, Weitao, Wipf, Peter
Published in Tetrahedron (31.03.2010)
Published in Tetrahedron (31.03.2010)
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Journal Article