Shaping proteostasis at the cellular, tissue, and organismal level
Sala, Ambre J, Bott, Laura C, Morimoto, Richard I
Published in The Journal of cell biology (01.05.2017)
Published in The Journal of cell biology (01.05.2017)
Get full text
Journal Article
Embryo integrity regulates maternal proteostasis and stress resilience
Sala, Ambre J, Bott, Laura C, Brielmann, Renee M, Morimoto, Richard I
Published in Genes & development (01.05.2020)
Published in Genes & development (01.05.2020)
Get full text
Journal Article
Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues
Sala, Ambre J, Grant, Rogan A, Imran, Ghania, Morton, Claire, Brielmann, Renee M, Gorgoń, Szymon, Watts, Jennifer, Bott, Laura C, Morimoto, Richard I
Published in Genes & development (25.06.2024)
Published in Genes & development (25.06.2024)
Get full text
Journal Article
A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy
Bott, Laura C, Badders, Nisha M, Chen, Ke-Lian, Harmison, George G, Bautista, Elaine, Shih, Charles C-Y, Katsuno, Masahisa, Sobue, Gen, Taylor, J Paul, Dantuma, Nico P, Fischbeck, Kenneth H, Rinaldi, Carlo
Published in Human molecular genetics (15.05.2016)
Published in Human molecular genetics (15.05.2016)
Get full text
Journal Article
MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy
Pourshafie, Naemeh, Lee, Philip R, Chen, Ke-lian, Harmison, George G, Bott, Laura C, Katsuno, Masahisa, Sobue, Gen, Burnett, Barrington G, Fischbeck, Kenneth H, Rinaldi, Carlo
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
Get full text
Journal Article
Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy
Rinaldi, Carlo, Bott, Laura C, Chen, Ke-lian, Harmison, George G, Katsuno, Masahisa, Sobue, Gen, Pennuto, Maria, Fischbeck, Kenneth H
Published in Molecular medicine (Cambridge, Mass.) (2012)
Published in Molecular medicine (Cambridge, Mass.) (2012)
Get full text
Journal Article
Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents
Pourshafie, Naemeh, Lee, Philip R, Chen, Ke-Lian, Harmison, George G, Bott, Laura C, Fischbeck, Kenneth H, Rinaldi, Carlo
Published in Journal of visualized experiments (10.08.2018)
Published in Journal of visualized experiments (10.08.2018)
Get full text
Journal Article
The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/CCdh1 ubiquitin ligase complex
Bott, Laura C., Salomons, Florian A., Maric, Dragan, Liu, Yuhong, Merry, Diane, Fischbeck, Kenneth H., Dantuma, Nico P.
Published in Scientific reports (17.06.2016)
Published in Scientific reports (17.06.2016)
Get full text
Journal Article
The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex
Bott, Laura C, Salomons, Florian A, Maric, Dragan, Liu, Yuhong, Merry, Diane, Fischbeck, Kenneth H, Dantuma, Nico P
Published in Scientific reports (17.06.2016)
Published in Scientific reports (17.06.2016)
Get full text
Journal Article
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
Svensson, Charlotte, Ceder, Jens, Iglesias-Gato, Diego, Chuan, Yin-Choy, Pang, See Tong, Bjartell, Anders, Martinez, Roxana Merino, Bott, Laura, Helczynski, Leszek, Ulmert, David, Wang, Yuzhuo, Niu, Yuanjie, Collins, Colin, Flores-Morales, Amilcar
Published in Nucleic acids research (01.01.2014)
Published in Nucleic acids research (01.01.2014)
Get full text
Journal Article
Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents
Pourshafie, Naemeh, Lee, Philip R., Chen, Ke-lian, Harmison, George G., Bott, Laura C., Fischbeck, Kenneth H., Rinaldi, Carlo
Published in Journal of visualized experiments (10.08.2018)
Published in Journal of visualized experiments (10.08.2018)
Get full text
Journal Article
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
Svensson, C., Ceder, J., Iglesias-Gato, D., Chuan, Y.-C., Pang, S. T., Bjartell, A., Martinez, R. M., Bott, L., Helczynski, L., Ulmert, D., Wang, Y., Niu, Y., Collins, C., Flores-Morales, A.
Published in Nucleic acids research (2014)
Published in Nucleic acids research (2014)
Get full text
Journal Article
Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia
Rinaldi, Carlo, Schmidt, Thomas, Situ, Alan J, Johnson, Janel O, Lee, Philip R, Chen, Ke-lian, Bott, Laura C, Fadó, Rut, Harmison, George H, Parodi, Sara, Grunseich, Christopher, Renvoisé, Benoît, Biesecker, Leslie G, DeMichele, Giuseppe, Santorelli, Filippo M, Filla, Alessandro, Stevanin, Giovanni, Dürr, Alexandra, Brice, Alexis, Casals, Núria, Traynor, Bryan J, Blackstone, Craig, Ulmer, Tobias S, Fischbeck, Kenneth H
Published in Archives of neurology (Chicago) (01.05.2015)
Get full text
Published in Archives of neurology (Chicago) (01.05.2015)
Journal Article