The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions
Abdulrahman, Basant A., Abdelaziz, Dalia, Thapa, Simrika, Lu, Li, Jain, Shubha, Gilch, Sabine, Proniuk, Stefan, Zukiwski, Alexander, Schatzl, Hermann M.
Published in Scientific reports (14.12.2017)
Published in Scientific reports (14.12.2017)
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Journal Article
Phase I study of onapristone, a type I antiprogestin, in female patients with previously treated recurrent or metastatic progesterone receptor-expressing cancers
Cottu, Paul H, Bonneterre, Jacques, Varga, Andrea, Campone, Mario, Leary, Alexandra, Floquet, Anne, Berton-Rigaud, Dominique, Sablin, Marie-Paule, Lesoin, Anne, Rezai, Keyvan, Lokiec, François M, Lhomme, Catherine, Bosq, Jacques, Bexon, Alice S, Gilles, Erard M, Proniuk, Stefan, Dieras, Veronique, Jackson, David M, Zukiwski, Alexander, Italiano, Antoine
Published in PloS one (10.10.2018)
Published in PloS one (10.10.2018)
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Journal Article
Phase II Multicenter, Open‐Label Study of Oral ENMD‐2076 for the Treatment of Patients with Advanced Fibrolamellar Carcinoma
Abou‐Alfa, Ghassan K., Mayer, Robert, Venook, Alan P., O'Neill, Allison F., Beg, Muhammad S., LaQuaglia, Michael, Kingham, Peter T., Kobos, Rachel, Basturk, Olca, Brennan, Cameron, Yopp, Adam, Harding, James J., Leong, Stephen, Crown, John, Hoti, Emir, Leonard, Gregory, Ly, Michele, Bradley, Mikaela, Valentino, Emily, Markowitz, David, Zukiwski, Alexander, Ren, Ken, Gordan, John D.
Published in The oncologist (Dayton, Ohio) (01.12.2020)
Published in The oncologist (Dayton, Ohio) (01.12.2020)
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Journal Article
Abstract 3471: Comparative assessment of in vitro activity and aactivated progesterone receptor (APR) biomarker predictivity for multiple antiprogestins
Zukiwski, Alexander, Gilles, Erard, Serin, Guillaume, Bosq, Jacques, Alleaume, Charline
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Exploring the in vitro potential of celecoxib derivative AR-12 as an effective antiviral compound against four dengue virus serotypes
Hassandarvish, Pouya, Oo, Adrian, Jokar, Amin, Zukiwski, Alexander, Proniuk, Stefan, Abu Bakar, Sazaly, Zandi, Keivan
Published in Journal of antimicrobial chemotherapy (01.09.2017)
Published in Journal of antimicrobial chemotherapy (01.09.2017)
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Journal Article
Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function
Booth, Laurence, Shuch, Brian, Albers, Thomas, Roberts, Jane L, Tavallai, Mehrad, Proniuk, Stefan, Zukiwski, Alexander, Wang, Dasheng, Chen, Ching-Shih, Bottaro, Don, Ecroyd, Heath, Lebedyeva, Iryna O, Dent, Paul
Published in Oncotarget (15.03.2016)
Published in Oncotarget (15.03.2016)
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Journal Article
Abstract P5-02-13: Triple negative breast cancer, the impact of isotype-specific progesterone receptor antibodies on the diagnosis results
Bonneterre, Jacques, Bosq, Jacques, Alleaume, Charline, Gilles, Erard, Jamme, Philippe, Zukiwski, Alexander
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Journal Article
Abstract P6-08-19: Activated form of the estrogen receptor α (ER) in breast cancer (BC) and its correlation with prognosis
Gilles, Erard, Bosq, Jacques, Alleaume, Charline, Zukiwski, Alexander, Hutt, Emile, Bonneterre, Jacques
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Journal Article
Abstract 5567: Impact of progesterone receptor (PR) isotype-specific immunohistochemistry (IHC) on the diagnosis of triple negative breast cancer (BC)
Gilles, Erard, Bosq, Jacques, Caplier, Laura, Bexon, Alice, Zukiwski, Alexander, Bonneterre, Jacques
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Clinical and pathologic correlation of the activated form of the androgen receptor (AR) in breast cancer (BC)
Jamme, Philippe, Bosq, Jacques, Gilles, Erard M., Zukiwski, Alexander, Alleaume, Charline, Gilles, Ambroise, Bonneterre, Jacques
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Clinical and pathologic correlation of the activated form of the estrogen receptor beta (ERβ) in breast cancer (BC)
Hutt, Emilie, Bosq, Jacques, Gilles, Erard M., Zukiwski, Alexander, Alleaume, Charline, Gilles, Barthelemy Octavius, Bonneterre, Jacques
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Abstract 1646: Synthesis of [11C]onapristone for clinical investigation
Madar, Olivier, Fouque, Julien, Proniuk, Stefan, Rezai, Keyvan, Huguet, Samuel, Zukiwski, Alexander, Gilles, Erard M., Bexon, Alice S., Lokiec, François
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 1317: Antiprogestin drug development: in vitro validation of a potential clinical biomarker
Gilles, Erard, Caplier, Laura, Valent, Alexander, Serin, Guillaume, Gompel, Anne, Bosq, Jacques, Zukiwski, Alexander
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Validation of a population pharmacokinetic (PPK) model for onapristone (ONA) in patients (pts) with cancer: Analysis of 2 clinical trials
Rezai, Keyvan, Huguet, Samuel, Bret, Fanny, Cottu, Paul H., Attard, Gerhardt, Italiano, Antoine, Varga, Andrea, Bonneterre, Jacques, Campone, Mario, Jayaram, Anuradha, Bexon, Alice Susannah, Gilles, Erard M., Proniuk, Stefan, Barranco, Charles, Zukiwski, Alexander, Lokiec, Francois Marc
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Phase 1-2 study of progesterone receptor (PR) inhibition with extended-release (ER) onapristone (ONA) alone or in combination with abiraterone (AA) in patients (pts) with castration-resistant prostate cancer (CRPC) incorporating plasma DNA analysis to define androgen receptor (AR) status
Jayaram, Anuradha, Nowakowska, Karolina, Mateo, Joaquin, Kumar, Sanjeev, Hernandez, Tatiana, Fulton, Ben, Nava Rodrigues, Daniel, Riisnaes, Ruth, Zukiwski, Alexander, Bexon, Alice Susannah, Proniuk, Stefan, Barranco, Charles, Bianchini, Diletta, Zafeirou, Zafeiris, Perez Lopez, Raquel, Tunariu, Nina, Pacey, Simon, Jones, Robert J., De Bono, Johann S., Attard, Gerhardt
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Abstract 4523: Population pharmacokinetic (PPK) modeling of onapristone in patients (pts) with progesterone receptor (PR)-expressing cancers
Rezai, Keyvan, Cottu, Paul, Huguet, Samuel, Campone, Mario, Italiano, Antoine, Varga, Andrea, Bonneterre, Jacques, Leary, Alexandra, Sablin, Marie-Paule, Proniuk, Stefan, Bexon, Alice, Gilles, Erard, Bisaha, Joseph, Zukiwski, Alexander, Lokiec, Francois
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 4512: Onapristone in patients (pts) with progesterone receptor (PR)-expressing cancers: PK results from part 1 of a randomized, parallel-dose phase 1 study
Lokiec, Francois, Italiano, Antoine, Varga, Andrea, Bonneterre, Jacques, Campone, Mario, Leary, Alexandra, Rezai, Keyvan, Sablin, Marie-Paule, Bexon, Alice, Proniuk, Stefan, Gilles, Erard, Bisaha, Joseph, Zukiwski, Alexander, Cottu, Paul
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Clinical and pathologic correlation of the activated form of the estrogen receptor (ER) in breast cancer (BC)
Bonneterre, Jacques, Gilles, Erard M., Zukiwski, Alexander A., Bosq, Jacques, Valent, Alexander, Hutt, Emilie, Fuqua, Suzanne A.W.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Identification of the activated form of the estrogen receptor (ER) in breast cancer (BC)
Gilles, Erard M., Bosq, Jacques, Fuqua, Suzanne A.W., Zukiwski, Alexander A., Caillaud, Jean-Michel, Gilles, Barthelemy, Bonneterre, Jacques
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Phase 1-2 study of progesterone receptor (PR) inhibition with extended-release (ER) onapristone (ONA) in patients (pts) with castration-resistant prostate cancer (CRPC): PK, safety and PR testing results from the dose escalation cohort
Jayaram, Anuradha, Nowakowska, Karolina, Mateo, Joaquin, Nava Rodrigues, Daniel, Riisnaes, Ruth, Zukiwski, Alexander, Proniuk, Stefan, Bexon, Alice Susannah, Bisaha, Joseph, Bianchini, Diletta, Zafeiriou, Zafeiris, Perez Lopez, Raquel, Tunariu, Nina, De Bono, Johann Sebastian, Attard, Gerhardt
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article