Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain
Han, Jinju, Kim, Hyung Joon, Schafer, Simon T., Paquola, Apua, Clemenson, Gregory D., Toda, Tomohisa, Oh, Jinseo, Pankonin, Aimee R., Lee, Bo Suk, Johnston, Stephen T., Sarkar, Anindita, Denli, Ahmet M., Gage, Fred H.
Published in Neuron (Cambridge, Mass.) (06.07.2016)
Published in Neuron (Cambridge, Mass.) (06.07.2016)
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An in vivo neuroimmune organoid model to study human microglia phenotypes
Schafer, Simon T., Mansour, Abed AlFatah, Schlachetzki, Johannes C.M., Pena, Monique, Ghassemzadeh, Saeed, Mitchell, Lisa, Mar, Amanda, Quang, Daphne, Stumpf, Sarah, Ortiz, Irene Santisteban, Lana, Addison J., Baek, Clara, Zaghal, Raghad, Glass, Christopher K., Nimmerjahn, Axel, Gage, Fred H.
Published in Cell (11.05.2023)
Published in Cell (11.05.2023)
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Journal Article
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
Mertens, Jerome, Herdy, Joseph R., Traxler, Larissa, Schafer, Simon T., Schlachetzki, Johannes C.M., Böhnke, Lena, Reid, Dylan A., Lee, Hyungjun, Zangwill, Dina, Fernandes, Diana P., Agarwal, Ravi K., Lucciola, Raffaella, Zhou-Yang, Lucia, Karbacher, Lukas, Edenhofer, Frank, Stern, Shani, Horvath, Steve, Paquola, Apua C.M., Glass, Christopher K., Yuan, Shauna H., Ku, Manching, Szücs, Attila, Goldstein, Lawrence S.B., Galasko, Douglas, Gage, Fred H.
Published in Cell stem cell (02.09.2021)
Published in Cell stem cell (02.09.2021)
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Journal Article
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Zhu, Zhe, Mesci, Pinar, Bernatchez, Jean A., Gimple, Ryan C., Wang, Xiuxing, Schafer, Simon T., Wettersten, Hiromi I., Beck, Sungjun, Clark, Alex E., Wu, Qiulian, Prager, Briana C., Kim, Leo J.Y., Dhanwani, Rekha, Sharma, Sonia, Garancher, Alexandra, Weis, Sara M., Mack, Stephen C., Negraes, Priscilla D., Trujillo, Cleber A., Penalva, Luiz O., Feng, Jing, Lan, Zhou, Zhang, Rong, Wessel, Alex W., Dhawan, Sanjay, Diamond, Michael S., Chen, Clark C., Wechsler-Reya, Robert J., Gage, Fred H., Hu, Hongzhen, Siqueira-Neto, Jair L., Muotri, Alysson R., Cheresh, David A., Rich, Jeremy N.
Published in Cell stem cell (06.02.2020)
Published in Cell stem cell (06.02.2020)
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Journal Article
Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells
Toda, Tomohisa, Hsu, Jonathan Y., Linker, Sara B., Hu, Lauren, Schafer, Simon T., Mertens, Jerome, Jacinto, Filipe V., Hetzer, Martin W., Gage, Fred H.
Published in Cell stem cell (02.11.2017)
Published in Cell stem cell (02.11.2017)
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Journal Article
A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
Jaeger, Baptiste N., Linker, Sara B., Parylak, Sarah L., Barron, Jerika J., Gallina, Iryna S., Saavedra, Christian D., Fitzpatrick, Conor, Lim, Christina K., Schafer, Simon T., Lacar, Benjamin, Jessberger, Sebastian, Gage, Fred H.
Published in Nature communications (06.08.2018)
Published in Nature communications (06.08.2018)
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Journal Article
Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
Krüger, Anne, Oldenburg, Marina, Chebrolu, Chiranjeevi, Beisser, Daniela, Kolter, Julia, Sigmund, Anna M, Steinmann, Jörg, Schäfer, Simon, Hochrein, Hubertus, Rahmann, Sven, Wagner, Hermann, Henneke, Philipp, Hornung, Veit, Buer, Jan, Kirschning, Carsten J
Published in EMBO reports (01.12.2015)
Published in EMBO reports (01.12.2015)
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Journal Article
Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation
Toda, Tomohisa, Bedrosian, Tracy A., Schafer, Simon T., Cuoco, Michael S., Linker, Sara B., Ghassemzadeh, Saeed, Mitchell, Lisa, Whiteley, Jack T., Novaresi, Nicole, McDonald, Aidan H., Gallina, Iryna S., Yoon, Hyojung, Hester, Mark E., Pena, Monique, Lim, Christina, Suljic, Emelia, AlFatah Mansour, Abed, Boulard, Matthieu, Parylak, Sarah L., Gage, Fred H.
Published in Cell reports (Cambridge) (27.02.2024)
Published in Cell reports (Cambridge) (27.02.2024)
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Journal Article
NGLY1 mutations cause protein aggregation in human neurons
Manole, Andreea, Wong, Thomas, Rhee, Amanda, Novak, Sammy, Chin, Shao-Ming, Tsimring, Katya, Paucar, Andres, Williams, April, Newmeyer, Traci Fang, Schafer, Simon T., Rosh, Idan, Kaushik, Susmita, Hoffman, Rene, Chen, Songjie, Wang, Guangwen, Snyder, Michael, Cuervo, Ana Maria, Andrade, Leo, Manor, Uri, Lee, Kevin, Jones, Jeffrey R., Stern, Shani, Marchetto, Maria C., Gage, Fred H.
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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Journal Article
AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study
Rump, Katharina, Unterberg, Matthias, Bergmann, Lars, Bankfalvi, Agnes, Menon, Anil, Schäfer, Simon, Scherag, André, Bazzi, Zainab, Siffert, Winfried, Peters, Jürgen, Adamzik, Michael
Published in Journal of translational medicine (21.11.2016)
Published in Journal of translational medicine (21.11.2016)
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Journal Article
Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons
Herdy, Joseph, Schafer, Simon, Kim, Yongsung, Ansari, Zoya, Zangwill, Dina, Ku, Manching, Paquola, Apua, Lee, Hyungjun, Mertens, Jerome, Gage, Fred H
Published in eLife (17.05.2019)
Published in eLife (17.05.2019)
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Journal Article
REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
Kim, Hyung Joon, Denli, Ahmet M, Wright, Rebecca, Baul, Tithi D, Clemenson, Gregory D, Morcos, Ari S, Zhao, Chunmei, Schafer, Simon T, Gage, Fred H, Kagalwala, Mohamedi N
Published in The Journal of neuroscience (04.11.2015)
Published in The Journal of neuroscience (04.11.2015)
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Journal Article
Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders
Bermperidis, Theodoros, Schafer, Simon, Gage, Fred H, Sejnowski, Terrence, Torres, Elizabeth B
Published in Frontiers in neuroscience (02.06.2022)
Published in Frontiers in neuroscience (02.06.2022)
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Journal Article
Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells
Soni, Abhinav, Klütsch, Diana, Hu, Xin, Houtman, Judith, Rund, Nicole, McCloskey, Asako, Mertens, Jerome, Schafer, Simon T, Amin, Hayder, Toda, Tomohisa
Published in Cells (Basel, Switzerland) (26.07.2021)
Published in Cells (Basel, Switzerland) (26.07.2021)
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Journal Article
The NFKB1 Promoter Polymorphism (―94ins/delATTG) Alters Nuclear Translocation of NF-κB1 in Monocytes after Lipopolysaccharide Stimulation and Is Associated with Increased Mortality in Sepsis
ADAMZIK, Michael, SCHAFER, Simon, SIFFERT, Winfried, PETERS, Jürgen, HARTMANN, Matthias, FREY, Ulrich H, BECKER, Arne, KREUZER, Maximiliane, WINNING, Sandra, FREDE, Stilla, STEINMANN, Jörg, FANDREY, Joachim, ZACHAROWSKI, Kai
Published in Anesthesiology (Philadelphia) (2013)
Published in Anesthesiology (Philadelphia) (2013)
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Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock
Schäfer, Simon T, Gessner, Sophia, Scherag, André, Rump, Katharina, Frey, Ulrich H, Siffert, Winfried, Westendorf, Astrid M, Steinmann, Jörg, Peters, Jürgen, Adamzik, Michael
Published in PloS one (18.08.2014)
Published in PloS one (18.08.2014)
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