Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets
Mann, Paul A, Müller, Anna, Wolff, Kerstin A, Fischmann, Thierry, Wang, Hao, Reed, Patricia, Hou, Yan, Li, Wenjin, Müller, Christa E, Xiao, Jianying, Murgolo, Nicholas, Sher, Xinwei, Mayhood, Todd, Sheth, Payal R, Mirza, Asra, Labroli, Marc, Xiao, Li, McCoy, Mark, Gill, Charles J, Pinho, Mariana G, Schneider, Tanja, Roemer, Terry
Published in PLoS pathogens (01.05.2016)
Published in PLoS pathogens (01.05.2016)
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Journal Article
Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species
MANN, Paul A, MCNICHOLAS, Paul M, CHAU, Andrew S, PATEL, Reena, MENDRICK, Cara, ULLMANN, Andrew J, CORNELY, Oliver A, PATINO, Hernando, BLACK, Todd A
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
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Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole
NASCIMENTO, Adriana M, GOLDMAN, Gustavo H, PARK, Steven, MAMAS, Salvatore A. E, DELMAS, Guillaume, OZA, Uma, LOLANS, Karen, DUDLEY, Michael N, MANN, Paul A, PERLIN, David S
Published in Antimicrobial Agents and Chemotherapy (01.05.2003)
Published in Antimicrobial Agents and Chemotherapy (01.05.2003)
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Mutations in Aspergillus fumigatus Resulting in Reduced Susceptibility to Posaconazole Appear To Be Restricted to a Single Amino Acid in the Cytochrome P450 14α-Demethylase
MANN, Paul A, PARMEGIANI, Raulo M, WEI, Shui-Qing, MENDRICK, Cara A, XIN LI, LOEBENBERG, David, DIDOMENICO, Beth, HARE, Roberta S, WALKER, Scott S, MCNICHOLAS, Paul M
Published in Antimicrobial Agents and Chemotherapy (01.02.2003)
Published in Antimicrobial Agents and Chemotherapy (01.02.2003)
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Journal Article
Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds
Munayyer, Hanan K, Mann, Paul A, Chau, Andrew S, Yarosh-Tomaine, Taisa, Greene, Jonathan R, Hare, Roberta S, Heimark, Larry, Palermo, Robert E, Loebenberg, David, McNicholas, Paul M
Published in Antimicrobial Agents and Chemotherapy (01.10.2004)
Published in Antimicrobial Agents and Chemotherapy (01.10.2004)
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Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins
Konovalova, Anna, Grabowicz, Marcin, Balibar, Carl J., Malinverni, Juliana C., Painter, Ronald E., Riley, Daniel, Mann, Paul A., Wang, Hao, Garlisi, Charles G., Sherborne, Brad, Rigel, Nathan W., Ricci, Dante P., Black, Todd A., Roemer, Terry, Silhavy, Thomas J., Walker, Scott S.
Published in Proceedings of the National Academy of Sciences - PNAS (10.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (10.07.2018)
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Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria
MCNICHOLAS, P. M, NAJARIAN, D. J, MANN, P. A, HESK, D, HARE, R. S, SHAW, K. J, BLACK, T. A
Published in Antimicrobial Agents and Chemotherapy (01.05.2000)
Published in Antimicrobial Agents and Chemotherapy (01.05.2000)
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EmtA, a rRNA methyltransferase conferring high‐level evernimicin resistance
Mann, Paul A., Xiong, Liqun, Mankin, Alexander S., Chau, Andrew S., Mendrick, Cara A., Najarian, David J., Cramer, Christina A., Loebenberg, David, Coates, Elizabeth, Murgolo, Nicholas J., Aarestrup, Frank M., Goering, Richard V., Black, Todd A., Hare, Roberta S., McNicholas, Paul M.
Published in Molecular microbiology (01.09.2001)
Published in Molecular microbiology (01.09.2001)
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Inhibitor of intramembrane protease RseP blocks the sE response causing lethal accumulation of unfolded outer membrane proteins
Konovalova, Anna, Grabowicz, Marcin, Balibar, Carl J, Malinverni, Juliana C, Painter, Ronald E, Riley, Daniel, Mann, Paul A, Wang, Hao, Garlisi, Charles G, Sherborne, Brad, Rigel, Nathan W, Ricci, Dante P, Black, Todd A, Roemer, Terry, Silhavy, Thomas J, Walker, Scott S
Published in Proceedings of the National Academy of Sciences - PNAS (10.07.2018)
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Published in Proceedings of the National Academy of Sciences - PNAS (10.07.2018)
Journal Article
Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds
Munayyer, Hanan K, Mann, Paul A, Chau, Andrew S, Yarosh-Tomaine, Taisa, Greene, Jonathan R, Hare, Roberta S, Heimark, Larry, Palermo, Robert E, Loebenberg, David, McNicholas, Paul M
Published in Antimicrobial agents and chemotherapy (01.10.2004)
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Published in Antimicrobial agents and chemotherapy (01.10.2004)
Journal Article
Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase
Mann, Paul A, Parmegiani, Raulo M, Wei, Shui-Qing, Mendrick, Cara A, Li, Xin, Loebenberg, David, DiDomenico, Beth, Hare, Roberta S, Walker, Scott S, McNicholas, Paul M
Published in Antimicrobial agents and chemotherapy (01.02.2003)
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Published in Antimicrobial agents and chemotherapy (01.02.2003)
Journal Article
Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins
RATHER, P. N, MUNAYYER, H, MANN, P. A, HARE, R. S, MILLER, G. H, SHAW, K. J
Published in Journal of Bacteriology (01.05.1992)
Published in Journal of Bacteriology (01.05.1992)
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