Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders
Bruns, Robert F., Mitchell, Stephen N., Wafford, Keith A., Harper, Alex J., Shanks, Elaine A., Carter, Guy, O'Neill, Michael J., Murray, Tracey K., Eastwood, Brian J., Schaus, John M., Beck, James P., Hao, Junliang, Witkin, Jeffrey M., Li, Xia, Chernet, Eyassu, Katner, Jason S., Wang, Hong, Ryder, John W., Masquelin, Meghane E., Thompson, Linda K., Love, Patrick L., Maren, Deanna L., Falcone, Julie F., Menezes, Michelle M., Zhang, Linli, Yang, Charles R., Svensson, Kjell A.
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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Journal Article
Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior
Ferris, Craig F., Lu, Shi-fang, Messenger, Tara, Guillon, Christophe D., Heindel, Ned, Miller, Marvin, Koppel, Gary, Robert Bruns, F., Simon, Neal G.
Published in Pharmacology, biochemistry and behavior (01.02.2006)
Published in Pharmacology, biochemistry and behavior (01.02.2006)
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Journal Article
Azetidinones as vasopressin V1a antagonists
Guillon, Christophe D., Koppel, Gary A., Brownstein, Michael J., Chaney, Michael O., Ferris, Craig F., Lu, Shi-fang, Fabio, Karine M., Miller, Marvin J., Heindel, Ned D., Hunden, David C., Cooper, Robin D.G., Kaldor, Stephen W., Skelton, Jeffrey J., Dressman, Bruce A., Clay, Michael P., Steinberg, Mitchell I., Bruns, Robert F., Simon, Neal G.
Published in Bioorganic & medicinal chemistry (01.03.2007)
Published in Bioorganic & medicinal chemistry (01.03.2007)
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Journal Article
Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists
Zarrinmayeh, Hamideh, Zimmerman, Dennis M., Cantrell, Buddy E., Schober, Douglas A., Bruns, Robert E., Gackenheimer, Susan L., Ornstein, Paul L., Hipskind, Philip A., Britton, Thomas C., Gehlert, Donald R.
Published in Bioorganic & medicinal chemistry letters (08.03.1999)
Published in Bioorganic & medicinal chemistry letters (08.03.1999)
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Journal Article
Inhibition of protein kinase C by calphostin C is light-dependent
Bruns, Robert F., Miller, F.Dean, Merriman, Ronald L., Howbert, J.Jeffry, Heath, William F., Kobayashi, Eiji, Takahashi, Isami, Tamaoki, Tatsuya, Nakano, Hirofumi
Published in Biochemical and biophysical research communications (15.04.1991)
Published in Biochemical and biophysical research communications (15.04.1991)
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Journal Article
A rapid filtration assay for soluble receptors using polyethylenimine-treated filters
Bruns, Robert F., Lawson-Wendling, Karen, Pugsley, Thomas A.
Published in Analytical biochemistry (01.07.1983)
Published in Analytical biochemistry (01.07.1983)
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Journal Article
Structure-activity relationships of a series of benzothiophene-derived NPY Y1 antagonists: Optimization of the C-2 side chain
Britton, Thomas C., Spinazze, Patrick G., Hipskind, Philip A., Zimmerman, Dennis M., Zarrinmayeh, Hamideh, Schober, Douglas A., Gehlert, Donald R., Bruns, Robert F.
Published in Bioorganic & medicinal chemistry letters (08.02.1999)
Published in Bioorganic & medicinal chemistry letters (08.02.1999)
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Journal Article
The Neuropeptide Y Y 1 Antagonist, 1229U91, A Potent Agonist for the Human Pancreatic Polypeptide-Preferring (NPY Y 4) Receptor
Schober, Douglas A, Van Abbema, Anne M, Smiley, David L, Bruns, Robert F, Gehlert, Donald R
Published in Peptides (New York, N.Y. : 1980) (1998)
Published in Peptides (New York, N.Y. : 1980) (1998)
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Journal Article
Species differences in affinities of non-peptide antagonists for substance P receptors
Gitter, B D, Waters, D C, Bruns, R F, Mason, N R, Nixon, J A, Howbert, J J
Published in European journal of pharmacology (17.05.1991)
Published in European journal of pharmacology (17.05.1991)
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Journal Article
Rapid parallel synthesis applied to the optimization of a series of potent nonpeptide neuropeptide Y-1 receptor antagonists
Siegel, Miles G., Chaney, Michael O., Bruns, Robert F., Clay, Michael P., Schober, Douglas A., Van Abbema, Anne M., Johnson, Douglas W., Cantrell, Buddy E., Hahn, Patric J., Hunden, David C., Gehlert, Donald R., Zarrinmayeh, Hamideh, Ornstein, Paul L., Zimmerman, Dennis M., Koppel, Gary A.
Published in Tetrahedron (24.09.1999)
Published in Tetrahedron (24.09.1999)
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Journal Article
Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists
Zimmerman, Dennis M., Cantrell, Buddy E., Smith, Edward C.R., Nixon, James A., Bruns, Robert F., Gitter, Bruce, Hipskind, Philip A., Ornstein, Paul L., Zarrinmayeh, Hamideh, Britton, Thomas C., Schober, Douglas A., Gehlert, Donald R.
Published in Bioorganic & medicinal chemistry letters (03.03.1998)
Published in Bioorganic & medicinal chemistry letters (03.03.1998)
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Journal Article
Diphenylpyrazolidinone and benzodiazepine cholecystokinin antagonists: A case of convergent evolution in medicinal chemistry
Howbert, J.Jeffry, Lobb, Karen L., Britton, Thomas C., Mason, Norman R., Bruns, Robert F.
Published in Bioorganic & medicinal chemistry letters (01.05.1993)
Published in Bioorganic & medicinal chemistry letters (01.05.1993)
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Journal Article
Characteristics of an adenosine A1 binding site in human placental membranes
WORK, C, HUTCHISON, K, MADHU PRASAD, BRUNS, R. F, FOX, I. H
Published in Archives of biochemistry and biophysics (1989)
Published in Archives of biochemistry and biophysics (1989)
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