Brain cell type-specific enhancer-promoter interactome maps and disease - risk association
Nott, Alexi, Holtman, Inge R, Coufal, Nicole G, Schlachetzki, Johannes C M, Yu, Miao, Hu, Rong, Han, Claudia Z, Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P, O'Connor, Carolyn, Nickl, Christian K, Schafer, Simon T, Shen, Zeyang, Rissman, Robert A, Brewer, James B, Gosselin, David, Gonda, David D, Levy, Michael L, Rosenfeld, Michael G, McVicker, Graham, Gage, Fred H, Ren, Bing, Glass, Christopher K
Published in Science (American Association for the Advancement of Science) (29.11.2019)
Published in Science (American Association for the Advancement of Science) (29.11.2019)
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Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain
Han, Jinju, Kim, Hyung Joon, Schafer, Simon T., Paquola, Apua, Clemenson, Gregory D., Toda, Tomohisa, Oh, Jinseo, Pankonin, Aimee R., Lee, Bo Suk, Johnston, Stephen T., Sarkar, Anindita, Denli, Ahmet M., Gage, Fred H.
Published in Neuron (Cambridge, Mass.) (06.07.2016)
Published in Neuron (Cambridge, Mass.) (06.07.2016)
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An in vivo neuroimmune organoid model to study human microglia phenotypes
Schafer, Simon T., Mansour, Abed AlFatah, Schlachetzki, Johannes C.M., Pena, Monique, Ghassemzadeh, Saeed, Mitchell, Lisa, Mar, Amanda, Quang, Daphne, Stumpf, Sarah, Ortiz, Irene Santisteban, Lana, Addison J., Baek, Clara, Zaghal, Raghad, Glass, Christopher K., Nimmerjahn, Axel, Gage, Fred H.
Published in Cell (11.05.2023)
Published in Cell (11.05.2023)
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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
Mertens, Jerome, Herdy, Joseph R., Traxler, Larissa, Schafer, Simon T., Schlachetzki, Johannes C.M., Böhnke, Lena, Reid, Dylan A., Lee, Hyungjun, Zangwill, Dina, Fernandes, Diana P., Agarwal, Ravi K., Lucciola, Raffaella, Zhou-Yang, Lucia, Karbacher, Lukas, Edenhofer, Frank, Stern, Shani, Horvath, Steve, Paquola, Apua C.M., Glass, Christopher K., Yuan, Shauna H., Ku, Manching, Szücs, Attila, Goldstein, Lawrence S.B., Galasko, Douglas, Gage, Fred H.
Published in Cell stem cell (02.09.2021)
Published in Cell stem cell (02.09.2021)
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Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Zhu, Zhe, Mesci, Pinar, Bernatchez, Jean A., Gimple, Ryan C., Wang, Xiuxing, Schafer, Simon T., Wettersten, Hiromi I., Beck, Sungjun, Clark, Alex E., Wu, Qiulian, Prager, Briana C., Kim, Leo J.Y., Dhanwani, Rekha, Sharma, Sonia, Garancher, Alexandra, Weis, Sara M., Mack, Stephen C., Negraes, Priscilla D., Trujillo, Cleber A., Penalva, Luiz O., Feng, Jing, Lan, Zhou, Zhang, Rong, Wessel, Alex W., Dhawan, Sanjay, Diamond, Michael S., Chen, Clark C., Wechsler-Reya, Robert J., Gage, Fred H., Hu, Hongzhen, Siqueira-Neto, Jair L., Muotri, Alysson R., Cheresh, David A., Rich, Jeremy N.
Published in Cell stem cell (06.02.2020)
Published in Cell stem cell (06.02.2020)
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Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
Reid, Dylan A, Reed, Patrick J, Schlachetzki, Johannes C M, Nitulescu, Ioana I, Chou, Grace, Tsui, Enoch C, Jones, Jeffrey R, Chandran, Sahaana, Lu, Ake T, McClain, Claire A, Ooi, Jean H, Wang, Tzu-Wen, Lana, Addison J, Linker, Sara B, Ricciardulli, Anthony S, Lau, Shong, Schafer, Simon T, Horvath, Steve, Dixon, Jesse R, Hah, Nasun, Glass, Christopher K, Gage, Fred H
Published in Science (American Association for the Advancement of Science) (02.04.2021)
Published in Science (American Association for the Advancement of Science) (02.04.2021)
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Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells
Toda, Tomohisa, Hsu, Jonathan Y., Linker, Sara B., Hu, Lauren, Schafer, Simon T., Mertens, Jerome, Jacinto, Filipe V., Hetzer, Martin W., Gage, Fred H.
Published in Cell stem cell (02.11.2017)
Published in Cell stem cell (02.11.2017)
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A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
Jaeger, Baptiste N., Linker, Sara B., Parylak, Sarah L., Barron, Jerika J., Gallina, Iryna S., Saavedra, Christian D., Fitzpatrick, Conor, Lim, Christina K., Schafer, Simon T., Lacar, Benjamin, Jessberger, Sebastian, Gage, Fred H.
Published in Nature communications (06.08.2018)
Published in Nature communications (06.08.2018)
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Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
Krüger, Anne, Oldenburg, Marina, Chebrolu, Chiranjeevi, Beisser, Daniela, Kolter, Julia, Sigmund, Anna M, Steinmann, Jörg, Schäfer, Simon, Hochrein, Hubertus, Rahmann, Sven, Wagner, Hermann, Henneke, Philipp, Hornung, Veit, Buer, Jan, Kirschning, Carsten J
Published in EMBO reports (01.12.2015)
Published in EMBO reports (01.12.2015)
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Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation
Toda, Tomohisa, Bedrosian, Tracy A., Schafer, Simon T., Cuoco, Michael S., Linker, Sara B., Ghassemzadeh, Saeed, Mitchell, Lisa, Whiteley, Jack T., Novaresi, Nicole, McDonald, Aidan H., Gallina, Iryna S., Yoon, Hyojung, Hester, Mark E., Pena, Monique, Lim, Christina, Suljic, Emelia, AlFatah Mansour, Abed, Boulard, Matthieu, Parylak, Sarah L., Gage, Fred H.
Published in Cell reports (Cambridge) (27.02.2024)
Published in Cell reports (Cambridge) (27.02.2024)
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NGLY1 mutations cause protein aggregation in human neurons
Manole, Andreea, Wong, Thomas, Rhee, Amanda, Novak, Sammy, Chin, Shao-Ming, Tsimring, Katya, Paucar, Andres, Williams, April, Newmeyer, Traci Fang, Schafer, Simon T., Rosh, Idan, Kaushik, Susmita, Hoffman, Rene, Chen, Songjie, Wang, Guangwen, Snyder, Michael, Cuervo, Ana Maria, Andrade, Leo, Manor, Uri, Lee, Kevin, Jones, Jeffrey R., Stern, Shani, Marchetto, Maria C., Gage, Fred H.
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study
Rump, Katharina, Unterberg, Matthias, Bergmann, Lars, Bankfalvi, Agnes, Menon, Anil, Schäfer, Simon, Scherag, André, Bazzi, Zainab, Siffert, Winfried, Peters, Jürgen, Adamzik, Michael
Published in Journal of translational medicine (21.11.2016)
Published in Journal of translational medicine (21.11.2016)
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Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons
Herdy, Joseph, Schafer, Simon, Kim, Yongsung, Ansari, Zoya, Zangwill, Dina, Ku, Manching, Paquola, Apua, Lee, Hyungjun, Mertens, Jerome, Gage, Fred H
Published in eLife (17.05.2019)
Published in eLife (17.05.2019)
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REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
Kim, Hyung Joon, Denli, Ahmet M, Wright, Rebecca, Baul, Tithi D, Clemenson, Gregory D, Morcos, Ari S, Zhao, Chunmei, Schafer, Simon T, Gage, Fred H, Kagalwala, Mohamedi N
Published in The Journal of neuroscience (04.11.2015)
Published in The Journal of neuroscience (04.11.2015)
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Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders
Bermperidis, Theodoros, Schafer, Simon, Gage, Fred H, Sejnowski, Terrence, Torres, Elizabeth B
Published in Frontiers in neuroscience (02.06.2022)
Published in Frontiers in neuroscience (02.06.2022)
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Targeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology
Werner, Anja, Schäfer, Simon, Zaytseva, Olga, Albert, Heike, Lux, Anja, Krištić, Jasminka, Pezer, Marija, Lauc, Gordan, Winkler, Thomas, Nimmerjahn, Falk
Published in iScience (24.09.2021)
Published in iScience (24.09.2021)
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Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells
Soni, Abhinav, Klütsch, Diana, Hu, Xin, Houtman, Judith, Rund, Nicole, McCloskey, Asako, Mertens, Jerome, Schafer, Simon T, Amin, Hayder, Toda, Tomohisa
Published in Cells (Basel, Switzerland) (26.07.2021)
Published in Cells (Basel, Switzerland) (26.07.2021)
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