Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools
Long, Jaclyn, Darroch, Peter, Wan, Kah Fei, Kong, Kok Choi, Ktistakis, Nicholas, Pyne, Nigel J, Pyne, Susan
Published in Biochemical journal (01.10.2005)
Published in Biochemical journal (01.10.2005)
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Synthesis of a rhodanine-based compound library targeting Bcl-XL and Mcl-1
Bernardo, Paul H., Sivaraman, Thirunavukkarasu, Wan, Kah-Fei, Xu, Jin, Krishnamoorthy, Janarthanan, Song, Chun Meng, Tian, Liming, Chin, Jasmine S. F., Lim, Diane S. W., Mok, Henry Y. K., Yu, Victor C., Tong, Joo Chuan, Chai, Christina L. L.
Published in Pure and applied chemistry (05.02.2011)
Published in Pure and applied chemistry (05.02.2011)
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Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Lim, Siew Pheng, Noble, Christian Guy, Seh, Cheah Chen, Soh, Tingjin Sherryl, El Sahili, Abbas, Chan, Grace Kar Yarn, Lescar, Julien, Arora, Rishi, Benson, Timothy, Nilar, Shahul, Manjunatha, Ujjini, Wan, Kah Fei, Dong, Hongping, Xie, Xuping, Shi, Pei-Yong, Yokokawa, Fumiaki
Published in PLoS pathogens (01.08.2016)
Published in PLoS pathogens (01.08.2016)
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Discovery of Dengue Virus NS4B Inhibitors
Wang, Qing-Yin, Dong, Hongping, Zou, Bin, Karuna, Ratna, Wan, Kah Fei, Zou, Jing, Susila, Agatha, Yip, Andy, Shan, Chao, Yeo, Kim Long, Xu, Haoying, Ding, Mei, Chan, Wai Ling, Gu, Feng, Seah, Peck Gee, Liu, Wei, Lakshminarayana, Suresh B, Kang, CongBao, Lescar, Julien, Blasco, Francesca, Smith, Paul W, Shi, Pei-Yong
Published in Journal of virology (01.08.2015)
Published in Journal of virology (01.08.2015)
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The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase
Estoppey, David, Lee, Chia Min, Janoschke, Marco, Lee, Boon Heng, Wan, Kah Fei, Dong, Hongping, Mathys, Philippe, Filipuzzi, Ireos, Schuhmann, Tim, Riedl, Ralph, Aust, Thomas, Galuba, Olaf, McAllister, Gregory, Russ, Carsten, Spiess, Martin, Bouwmeester, Tewis, Bonamy, Ghislain M.C., Hoepfner, Dominic
Published in Cell reports (Cambridge) (18.04.2017)
Published in Cell reports (Cambridge) (18.04.2017)
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Lead Optimization of Spiropyrazolopyridones: A New and Potent Class of Dengue Virus Inhibitors
Zou, Bin, Chan, Wai Ling, Ding, Mei, Leong, Seh Yong, Nilar, Shahul, Seah, Peck Gee, Liu, Wei, Karuna, Ratna, Blasco, Francesca, Yip, Andy, Chao, Alex, Susila, Agatha, Dong, Hongping, Wang, Qing Yin, Xu, Hao Ying, Chan, Katherine, Wan, Kah Fei, Gu, Feng, Diagana, Thierry T, Wagner, Trixie, Dix, Ina, Shi, Pei-Yong, Smith, Paul W
Published in ACS medicinal chemistry letters (12.03.2015)
Published in ACS medicinal chemistry letters (12.03.2015)
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Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign
Smith, Thomas M, Lim, Siew Pheng, Yue, Kimberley, Busby, Scott A, Arora, Rishi, Seh, Cheah Chen, Wright, S Kirk, Nutiu, Razvan, Niyomrattanakit, Pornwaratt, Wan, Kah Fei, Beer, David, Shi, Pei-Yong, Benson, Timothy E
Published in Journal of biomolecular screening (01.01.2015)
Published in Journal of biomolecular screening (01.01.2015)
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Differential scanning fluorimetry as secondary screening platform for small molecule inhibitors of Bcl-XL
Wan, Kah Fei, Wang, Sifang, Brown, Christopher J., Yu, Victor C., Entzeroth, Michael, Lane, David P., Lee, May Ann
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
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Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections
Rao, Srinivasa P S, Gould, Matthew K, Noeske, Jonas, Saldivia, Manuel, Jumani, Rajiv S, Ng, Pearly S, René, Olivier, Chen, Yen-Liang, Kaiser, Marcel, Ritchie, Ryan, Francisco, Amanda Fortes, Johnson, Nila, Patra, Debjani, Cheung, Harry, Deniston, Colin, Schenk, Andreas D, Cortopassi, Wilian A, Schmidt, Remo S, Wiedemar, Natalie, Thomas, Bryanna, Palkar, Rima, Ghafar, Nahdiyah A, Manoharan, Vanessa, Luu, Catherine, Gable, Jonathan E, Wan, Kah Fei, Myburgh, Elmarie, Mottram, Jeremy C, Barnes, Whitney, Walker, John, Wartchow, Charles, Aziz, Natasha, Osborne, Colin, Wagner, Juergen, Sarko, Christopher, Kelly, John M, Manjunatha, Ujjini H, Mäser, Pascal, Jiricek, Jan, Lakshminarayana, Suresh B, Barrett, Michael P, Diagana, Thierry T
Published in Science (American Association for the Advancement of Science) (30.06.2023)
Published in Science (American Association for the Advancement of Science) (30.06.2023)
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Differential scanning fluorimetry as secondary screening platform for small molecule inhibitors of Bcl-X L
Wan, Kah Fei, Wang, Sifang, Brown, Christopher J., Yu, Victor C., Entzeroth, Michael, Lane, David P., Lee, May Ann
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
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Journal Article
Identification of covalent active site inhibitors of dengue virus protease
Koh-Stenta, Xiaoying, Joy, Joma, Wang, Si Fang, Kwek, Perlyn Zekui, Wee, John Liang Kuan, Wan, Kah Fei, Gayen, Shovanlal, Chen, Angela Shuyi, Kang, CongBao, Lee, May Ann, Poulsen, Anders, Vasudevan, Subhash G, Hill, Jeffrey, Nacro, Kassoum
Published in Drug design, development and therapy (01.01.2015)
Published in Drug design, development and therapy (01.01.2015)
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The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor
Wan, Kah Fei, Sambi, Balwinder S, Tate, Rothwelle, Waters, Catherine, Pyne, Nigel J
Published in The Journal of biological chemistry (16.05.2003)
Published in The Journal of biological chemistry (16.05.2003)
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The Inhibitory γ Subunit of the Type 6 Retinal cGMP Phosphodiesterase Functions to Link c-Src and G-protein-coupled Receptor Kinase 2 in a Signaling Unit That Regulates p42/p44 Mitogen-activated Protein Kinase by Epidermal Growth Factor
Kah Fei Wan, Balwinder S. Sambi, Rothwelle Tate, Catherine Waters, Nigel J. Pyne
Published in The Journal of biological chemistry (16.05.2003)
Published in The Journal of biological chemistry (16.05.2003)
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Journal Article
The Inhibitory γ Subunit of the Type 6 Retinal Cyclic Guanosine Monophosphate Phosphodiesterase Is a Novel Intermediate Regulating p42/p44 Mitogen-activated Protein Kinase Signaling in Human Embryonic Kidney 293 Cells
Wan, Kah Fei, Sambi, Balwinder S., Frame, Mhairi, Tate, Rothwelle, Pyne, Nigel J.
Published in The Journal of biological chemistry (12.10.2001)
Published in The Journal of biological chemistry (12.10.2001)
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Journal Article
The Inhibitory γ Subunit of the Type 6 Retinal Cyclic Guanosine Monophosphate Phosphodiesterase Is a Novel Intermediate Regulating p42/p44 Mitogen-activated Protein Kinase Signaling in Human Embryonic Kidney 293 Cells
Kah Fei Wan, Balwinder S. Sambi, Mhairi Frame, Rothwelle Tate, Nigel J. Pyne
Published in The Journal of biological chemistry (12.10.2001)
Published in The Journal of biological chemistry (12.10.2001)
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