The host STING pathway at the interface of cancer and immunity
Corrales, Leticia, McWhirter, Sarah M, Dubensky, Jr, Thomas W, Gajewski, Thomas F
Published in The Journal of clinical investigation (01.07.2016)
Published in The Journal of clinical investigation (01.07.2016)
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Journal Article
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
Corrales, Leticia, Glickman, Laura Hix, McWhirter, Sarah M., Kanne, David B., Sivick, Kelsey E., Katibah, George E., Woo, Seng-Ryong, Lemmens, Edward, Banda, Tamara, Leong, Justin J., Metchette, Ken, Dubensky, Thomas W., Gajewski, Thomas F.
Published in Cell reports (Cambridge) (19.05.2015)
Published in Cell reports (Cambridge) (19.05.2015)
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Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study
Meric-Bernstam, Funda, Sweis, Randy F, Kasper, Stefan, Hamid, Omid, Bhatia, Shailender, Dummer, Reinhard, Stradella, Agostina, Long, Georgina V, Spreafico, Anna, Shimizu, Toshio, Steeghs, Neeltje, Luke, Jason J, McWhirter, Sarah M, Müller, Thomas, Nair, Nitya, Lewis, Nancy, Chen, Xinhui, Bean, Andrew, Kattenhorn, Lisa, Pelletier, Marc, Sandhu, Shahneen
Published in Clinical cancer research (04.01.2023)
Published in Clinical cancer research (04.01.2023)
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Journal Article
Induction of type I interferons by bacteria
Monroe, Kathryn M., McWhirter, Sarah M., Vance, Russell E.
Published in Cellular microbiology (01.07.2010)
Published in Cellular microbiology (01.07.2010)
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Journal Article
STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection
Van Dis, Erik, Sogi, Kimberly M., Rae, Chris S., Sivick, Kelsey E., Surh, Natalie H., Leong, Meredith L., Kanne, David B., Metchette, Ken, Leong, Justin J., Bruml, Jacob R., Chen, Vivian, Heydari, Kartoosh, Cadieux, Nathalie, Evans, Tom, McWhirter, Sarah M., Dubensky, Thomas W., Portnoy, Daniel A., Stanley, Sarah A.
Published in Cell reports (Cambridge) (01.05.2018)
Published in Cell reports (Cambridge) (01.05.2018)
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Journal Article
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
McWhirter, Sarah M, Barbalat, Roman, Monroe, Kathryn M, Fontana, Mary F, Hyodo, Mamoru, Joncker, Nathalie T, Ishii, Ken J, Akira, Shizuo, Colonna, Marco, Chen, Zhijian J, Fitzgerald, Katherine A, Hayakawa, Yoshihiro, Vance, Russell E
Published in The Journal of experimental medicine (31.08.2009)
Published in The Journal of experimental medicine (31.08.2009)
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Journal Article
Interferon Regulatory Factor 3 Is Regulated by a Dual Phosphorylation-dependent Switch
Panne, Daniel, McWhirter, Sarah M., Maniatis, Tom, Harrison, Stephen C.
Published in The Journal of biological chemistry (03.08.2007)
Published in The Journal of biological chemistry (03.08.2007)
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Journal Article
IFN-Regulatory Factor 3-Dependent Gene Expression Is Defective in Tbk1-Deficient Mouse Embryonic Fibroblasts
McWhirter, Sarah M., Fitzgerald, Katherine A., Rosains, Jacqueline, Rowe, Daniel C., Golenbock, Douglas T., Maniatis, Tom
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2004)
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Journal Article
MK5 activates Rag transcription via Foxo1 in developing B cells
Chow, Kwan T, Timblin, Greg A, McWhirter, Sarah M, Schlissel, Mark S
Published in The Journal of experimental medicine (29.07.2013)
Published in The Journal of experimental medicine (29.07.2013)
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Journal Article
Gfi1 and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro
Chow, Kwan T, Schulz, Danae, McWhirter, Sarah M, Schlissel, Mark S
Published in PloS one (24.09.2013)
Published in PloS one (24.09.2013)
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Journal Article
Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas
Meric-Bernstam, Funda, Sweis, Randy F, Hodi, F Stephen, Messersmith, Wells A, Andtbacka, Robert H I, Ingham, Matthew, Lewis, Nancy, Chen, Xinhui, Pelletier, Marc, Chen, Xueying, Wu, Jincheng, McWhirter, Sarah M, Müller, Thomas, Nair, Nitya, Luke, Jason J
Published in Clinical cancer research (15.02.2022)
Published in Clinical cancer research (15.02.2022)
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Journal Article
Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.
Published in Cell reports (Cambridge) (11.12.2018)
Published in Cell reports (Cambridge) (11.12.2018)
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Journal Article
Synergy of a STING agonist and an IL-2 superkine in cancer immunotherapy against MHC I-deficient and MHC I + tumors
Wolf, Natalie K, Blaj, Cristina, Picton, Lora K, Snyder, Gail, Zhang, Li, Nicolai, Christopher J, Ndubaku, Chudi O, McWhirter, Sarah M, Garcia, K Christopher, Raulet, David H
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2022)
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Journal Article
Mucosal Vaccination with Cyclic Dinucleotide Adjuvants Induces Effective T Cell Homing and IL-17-Dependent Protection against Mycobacterium tuberculosis Infection
Jong, Robyn M, Van Dis, Erik, Berry, Samuel B, Nguyenla, Xammy, Baltodano, Alexander, Pastenkos, Gabrielle, Xu, Chenling, Fox, Douglas, Yosef, Nir, McWhirter, Sarah M, Stanley, Sarah A
Published in The Journal of immunology (1950) (15.01.2022)
Published in The Journal of immunology (1950) (15.01.2022)
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