Target engagement and drug residence time can be observed in living cells with BRET
Robers, Matthew B., Dart, Melanie L., Woodroofe, Carolyn C., Zimprich, Chad A., Kirkland, Thomas A., Machleidt, Thomas, Kupcho, Kevin R., Levin, Sergiy, Hartnett, James R., Zimmerman, Kristopher, Niles, Andrew L., Ohana, Rachel Friedman, Daniels, Danette L., Slater, Michael, Wood, Monika G., Cong, Mei, Cheng, Yi-Qiang, Wood, Keith V.
Published in Nature communications (03.12.2015)
Published in Nature communications (03.12.2015)
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Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction
Jaskula-Sztul, Renata, Eide, Jacob, Tesfazghi, Sara, Dammalapati, Ajitha, Harrison, April D, Yu, Xiao-Min, Scheinebeck, Casi, Winston-McPherson, Gabrielle, Kupcho, Kevin R, Robers, Matthew B, Hundal, Amrit K, Tang, Weiping, Chen, Herbert
Published in Molecular cancer therapeutics (01.02.2015)
Published in Molecular cancer therapeutics (01.02.2015)
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Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2
Jackson, Denise E., Kupcho, Kevin R., Newman, Peter. J.
Published in The Journal of biological chemistry (03.10.1997)
Published in The Journal of biological chemistry (03.10.1997)
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Abstract 1933: Improved DAMP assays for the in vitro assessment of immunogenic cell death
Niles, Andrew L., Kupcho, Kevin R., Lazar, Dan F., Cali, James J.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 710: Real-time apoptosis and necrosis detection in 3D spheroid cellmodels
Niles, Andrew L., Kupcho, Kevin R., Riss, Terry L., Lazar, Dan F., Cali, James J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 5595: Rapid and sensitive determination of cytokine release from cells without the need for sample transfer
Lazar, Dan F., Kupcho, Kevin R., Sondgeroth, Casey A., Thompson, David V., O'Brien, Martha A., Gilden, Julia K., Hsiao, Kevin, Cali, James J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Rapid and sensitive determination of cytokine release from cells without the need for sample transfer
Lazar, Dan F, Kupcho, Kevin R, Sondgeroth, Casey A, Hsiao, Kevin, Thompson, David V, O’Brien, Martha A, Gilden, Julia K, Cali, James J
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Abstract 4237: Isoenzyme-selective HDAC activity assays
Kupcho, Kevin R., Evans, Nathan J., Niles, Andrew L., Lazar, Dan F., Kirkland, Thomas A.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 3731: Luminescent cell health assays for tumor spheroid evaluation
Valley, Michael P., Kupcho, Kevin R., Zimprich, Chad A., Niles, Andrew L., Cali, James J., Kelm, Jens M., Moritz, Wolfgang, Lazar, Dan F.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Fluorescent cascade and direct assays for characterization of RAF signaling pathway inhibitors
Kupcho, Kevin R, Bruinsma, Rica, Hallis, Tina M, Lasky, David A, Somberg, Richard L, Turek-Etienne, Tammy, Vogel, Kurt W, Huwiler, Kristin G
Published in Current chemical genomics (25.02.2008)
Published in Current chemical genomics (25.02.2008)
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