Spectroscopic Detection of Transient Thiamin Diphosphate-Bound Intermediates on Benzoylformate Decarboxylase
Sergienko, Eduard A, Wang, Jue, Polovnikova, Lena, Hasson, Miriam S, McLeish, Michael J, Kenyon, George L, Jordan, Frank
Published in Biochemistry (Easton) (14.11.2000)
Published in Biochemistry (Easton) (14.11.2000)
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Journal Article
Mutagenesis of Two Acidic Active Site Residues in Human Muscle Creatine Kinase: Implications for the Catalytic Mechanism
Cantwell, John S, Novak, Walter R, Wang, Pan-Fen, McLeish, Michael J, Kenyon, George L, Babbitt, Patricia C
Published in Biochemistry (Easton) (13.03.2001)
Published in Biochemistry (Easton) (13.03.2001)
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Journal Article
An Unusually Low pK a for Cys282 in the Active Site of Human Muscle Creatine Kinase
Wang, Pan-Fen, McLeish, Michael J, Kneen, Malea M, Lee, Gavin, Kenyon, George L
Published in Biochemistry (Easton) (02.10.2001)
Published in Biochemistry (Easton) (02.10.2001)
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Journal Article
Structural Analysis of the Heparin-Binding Site of the NC1 Domain of Collagen XIV by CD and NMR
Montserret, Roland, Aubert-Foucher, Elisabeth, McLeish, Michael J., Hill, Joanna M., Ficheux, Damien, Jaquinod, Michel, van der Rest, Michel, Deléage, Gilbert, Penin, François
Published in Biochemistry (Easton) (18.05.1999)
Published in Biochemistry (Easton) (18.05.1999)
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Journal Article
An Unusually Low pKa for Cys282 in the Active Site of Human Muscle Creatine Kinase
WANG, Pan-Fen, MCLEISH, Michael J., KNEEN, Malea M., LEE, Gavin, KENYON, George L.
Published in Biochemistry (Easton) (02.10.2001)
Published in Biochemistry (Easton) (02.10.2001)
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Journal Article
The Crystal Structure of Benzoylformate Decarboxylase at 1.6 Å Resolution: Diversity of Catalytic Residues in Thiamin Diphosphate-Dependent Enzymes
Hasson, Miriam S, Muscate, Angelika, McLeish, Michael J, Polovnikova, Lena S, Gerlt, John A, Kenyon, George L, Petsko, Gregory A, Ringe, Dagmar
Published in Biochemistry (Easton) (14.07.1998)
Published in Biochemistry (Easton) (14.07.1998)
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Journal Article
The 2.1 Å Structure of Torpedo californica Creatine Kinase Complexed with the ADP-Mg2+−NO3 -−Creatine Transition-State Analogue Complex
Lahiri, Sushmita D, Wang, Pan-Fen, Babbitt, Patricia C, McLeish, Michael J, Kenyon, George L, Allen, Karen N
Published in Biochemistry (Easton) (26.11.2002)
Published in Biochemistry (Easton) (26.11.2002)
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Journal Article
The crystal structure of benzoylformate decarboxylase at 1.6 Angstrom resolution: Diversity of catalytic residues in thiamin diphosphate-dependent enzymes
Hasson, MS, Muscate, A, McLeish, MJ, Polovnikova, L S, Gerlt, JA, Kenyon, G L, Petsko, G A, Ringe, D
Published in Biochemistry (Easton) (14.07.1998)
Published in Biochemistry (Easton) (14.07.1998)
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Journal Article
Structural and Kinetic Analysis of Catalysis by a Thiamin Diphosphate-Dependent Enzyme, Benzoylformate Decarboxylase
Polovnikova, Elena S, McLeish, Michael J, Sergienko, Eduard A, Burgner, John T, Anderson, Natalie L, Bera, Asim K, Jordan, Frank, Kenyon, George L, Hasson, Miriam S
Published in Biochemistry (Easton) (25.02.2003)
Published in Biochemistry (Easton) (25.02.2003)
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Inhibitors of phenylethanolamine N-methyltransferase that are predicted to penetrate the blood-brain barrier: Design, synthesis, and evaluation of 3-fluoromethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinolines that possess low affinity toward the alpha(2)-adrenoceptor
Romero, FA, Vodonick, SM, Criscione, KR, McLeish, MJ, Grunewald, GL
Published in Journal of medicinal chemistry (26.08.2004)
Published in Journal of medicinal chemistry (26.08.2004)
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Journal Article
Mechanism-Based Inactivation of Thioredoxin Reductase from Plasmodium falciparum by Mannich Bases. Implication for Cytotoxicity
Davioud-Charvet, Elisabeth, McLeish, Michael J, Veine, Donna M, Giegel, David, Arscott, L. David, Andricopulo, Adriano D, Becker, Katja, Müller, Sylke, Schirmer, R. Heiner, Williams, Charles H, Kenyon, George L
Published in Biochemistry (Easton) (18.11.2003)
Published in Biochemistry (Easton) (18.11.2003)
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Journal Article
Structural, Mutagenic, and Kinetic Analysis of the Binding of Substrates and Inhibitors of Human Phenylethanolamine N-Methyltransferase
Wu, Qian, Gee, Christine L, Lin, Frank, Tyndall, Joel D, Martin, Jennifer L, Grunewald, Gary L, McLeish, Michael J
Published in Journal of medicinal chemistry (17.11.2005)
Published in Journal of medicinal chemistry (17.11.2005)
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Journal Article
Mode of Binding of Methyl Acceptor Substrates to the Adrenaline-Synthesizing Enzyme Phenylethanolamine N-Methyltransferase: Implications for Catalysis
Gee, Christine L, Tyndall, Joel D. A, Grunewald, Gary L, Wu, Qian, McLeish, Michael J, Martin, Jennifer L
Published in Biochemistry (Easton) (27.12.2005)
Published in Biochemistry (Easton) (27.12.2005)
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Journal Article
Isoleucine 69 and Valine 325 Form a Specificity Pocket in Human Muscle Creatine Kinase
Novak, Walter R. P, Wang, Pan-Fen, McLeish, Michael J, Kenyon, George L, Babbitt, Patricia C
Published in Biochemistry (Easton) (02.11.2004)
Published in Biochemistry (Easton) (02.11.2004)
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