Genetics of P450 Oxidoreductase: Sequence Variation in 842 Individuals of Four Ethnicities and Activities of 15 Missense Mutations
Huang, Ningwu, Agrawal, Vishal, Giacomini, Kathleen M., Miller, Walter L.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2008)
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Journal Article
Discovery of ravidasvir (PPI-668) as a potent pan-genotypic HCV NS5A inhibitor
Zhong, Min, Peng, Eric, Huang, Ningwu, Huang, Qi, Huq, Anja, Lau, Meiyen, Colonno, Richard, Li, Leping
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
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Journal Article
Severe Combined Adrenal and Gonadal Deficiency Caused by Novel Mutations in the Cholesterol Side Chain Cleavage Enzyme, P450scc
Kim, Chan Jong, Lin, Lin, Huang, Ningwu, Quigley, Charmian A, AvRuskin, Theodore W, Achermann, John C, Miller, Walter L
Published in The journal of clinical endocrinology and metabolism (01.03.2008)
Published in The journal of clinical endocrinology and metabolism (01.03.2008)
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Journal Article
Diversity and Function of Mutations in P450 Oxidoreductase in Patients with Antley-Bixler Syndrome and Disordered Steroidogenesis
Huang, Ningwu, Pandey, Amit V., Agrawal, Vishal, Reardon, William, Lapunzina, Pablo D., Mowat, David, Jabs, Ethylin Wang, Vliet, Guy Van, Sack, Joseph, Flück, Christa E., Miller, Walter L.
Published in American journal of human genetics (01.05.2005)
Published in American journal of human genetics (01.05.2005)
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Journal Article
Extraadrenal 21-Hydroxylation by CYP2C19 and CYP3A4: Effect on 21-Hydroxylase Deficiency
Gomes, Larissa G, Huang, Ningwu, Agrawal, Vishal, Mendonça, Berenice B, Bachega, Tania A. S. S, Miller, Walter L
Published in The journal of clinical endocrinology and metabolism (01.01.2009)
Published in The journal of clinical endocrinology and metabolism (01.01.2009)
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Journal Article
Genetic variation in human P450 oxidoreductase
Miller, Walter L., Huang, Ningwu, Agrawal, Vishal, Giacomini, Kathleen M.
Published in Molecular and cellular endocrinology (05.03.2009)
Published in Molecular and cellular endocrinology (05.03.2009)
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Journal Article
Apparent Manifesting Heterozygosity in P450 Oxidoreductase Deficiency and Its Effect on Coexisting 21-Hydroxylase Deficiency
Scott, Rachel R, Gomes, Larissa G, Huang, Ningwu, Van Vliet, Guy, Miller, Walter L
Published in The journal of clinical endocrinology and metabolism (01.06.2007)
Published in The journal of clinical endocrinology and metabolism (01.06.2007)
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Journal Article
Potent bisimidazole-based HCV NS5A inhibitors bearing annulated tricyclic motifs
Zhong, Min, Peng, Eric, Huang, Ningwu, Huang, Qi, Huq, Anja, Lau, Meiyen, Colonno, Richard, Li, Leping
Published in Bioorganic & medicinal chemistry letters (15.12.2014)
Published in Bioorganic & medicinal chemistry letters (15.12.2014)
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Journal Article
The Common P450 Oxidoreductase Variant A503V Is Not a Modifier Gene for 21-Hydroxylase Deficiency
Gomes, Larissa G, Huang, Ningwu, Agrawal, Vishal, Mendonça, Berenice B, Bachega, Tania A. S. S, Miller, Walter L
Published in The journal of clinical endocrinology and metabolism (01.07.2008)
Published in The journal of clinical endocrinology and metabolism (01.07.2008)
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Journal Article
Discovery of novel potent HCV NS5B polymerase non-nucleoside inhibitors bearing a fused benzofuran scaffold
Zhong, Min, Peng, Eric, Huang, Ningwu, Huang, Qi, Huq, Anja, Lau, Meiyen, Colonno, Richard, Li, Leping
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
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Journal Article
Abstract 2472: Inhibition of ENPP1 catalyzed ATP and cGAMP hydrolysis and in vivo antitumor efficacy of RBS2418 in the Hepa1-6 and GL261-luc syngeneic liver and glioblastoma mouse models
Huang, Ningwu, Cheng, Junjun, Hawley, Ron, Klumpp, Klaus
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Chemical synthesis of 4 '-thio and 4 '-sulfinyl pyrimidine nucleoside analogues
Guinan, Mieke, Huang, Ningwu, Hawes, Chris S., Lima, Marcelo A., Smith, Mark, Miller, Gavin J.
Published in Organic & biomolecular chemistry (16.02.2022)
Published in Organic & biomolecular chemistry (16.02.2022)
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Journal Article
First-in-human experience using RBS2418, an oral ENPP1 inhibitor within an expanded access protocol in combination with pembrolizumab in a patient with metastatic adrenal cancer
Csiki, Ildiko, Dong, Aiwen, Tuan, Bertrand Y., John, Elizabeth, O'Toole, Leslie, Seppa, Judy, Huang, Ningwu, Hawley, Ronald C., Exon, Chris, Glenn, Jeffrey S., Klumpp, Klaus
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Discovery of functionalized bisimidazoles bearing cyclic aliphatic-phenyl motifs as HCV NS5A inhibitors
Zhong, Min, Peng, Eric, Huang, Ningwu, Huang, Qi, Huq, Anja, Lau, Meiyen, Colonno, Richard, Li, Leping
Published in Bioorganic & medicinal chemistry letters (15.12.2014)
Published in Bioorganic & medicinal chemistry letters (15.12.2014)
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Journal Article