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Development of an AI-Assisted Embryo Selection System Using Iberian Ribbed Newts for Embryo-Fetal Development Toxicity Testing
Saiki, Naofumi, Adachi, Akiko, Ohnishi, Hiroshi, Koga, Atsuro, Ueki, Masaru, Kohno, Kiyotaka, Hayashi, Toshinori, Ohbayashi, Tetsuya
Published in YONAGO ACTA MEDICA (2024)
Published in YONAGO ACTA MEDICA (2024)
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Journal Article
Rethinking developmental toxicity testing: Evolution or revolution?
Scialli, Anthony R., Daston, George, Chen, Connie, Coder, Prägati S., Euling, Susan Y., Foreman, Jennifer, Hoberman, Alan M., Hui, Julia, Knudsen, Thomas, Makris, Susan L., Morford, LaRonda, Piersma, Aldert H., Stanislaus, Dinesh, Thompson, Kary E.
Published in Birth defects research (01.06.2018)
Published in Birth defects research (01.06.2018)
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Journal Article
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects
Theunissen, Peter T., Beken, Sonja, Beyer, Bruce K., Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, De Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Hui, Julia Y., Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matt, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.
Published in Critical reviews in toxicology (25.11.2016)
Published in Critical reviews in toxicology (25.11.2016)
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Journal Article
Testing strategies for embryo-fetal toxicity of human pharmaceuticals. Animal models vs. in vitro approaches: a workshop report
van der Laan, Jan Willem, Chapin, Robert E, Haenen, Bert, Jacobs, Abigail C, Piersma, Aldert
Published in Regulatory toxicology and pharmacology (01.06.2012)
Published in Regulatory toxicology and pharmacology (01.06.2012)
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Journal Article
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects
Theunissen, Peter T., Beken, Sonia, Beyer, Bruce, Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, de Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Y. Hui, Julia, Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matthew, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.
Published in Critical reviews in toxicology (28.05.2017)
Published in Critical reviews in toxicology (28.05.2017)
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Journal Article
Species-specific developmental toxicity in rats and rabbits: Generation of a reference compound list for development of alternative testing approaches
Teixidó, E., Krupp, E., Amberg, A., Czich, A., Scholz, S.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.03.2018)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.03.2018)
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Journal Article
Evaluation of rat and rabbit embryofetal development studies with pharmaceuticals: the added value of a second species
Roos, Puck, Anggasta, Caroline, Piersma, Aldert H, van Meer, Peter J K, Theunissen, Peter T
Published in Critical reviews in toxicology (20.10.2024)
Published in Critical reviews in toxicology (20.10.2024)
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Journal Article
Validation, Optimization, and Application of the Zebrafish Developmental Toxicity Assay for Pharmaceuticals Under the ICH S5(R3) Guideline
Song, Yi-Sheng, Dai, Ming-Zhu, Zhu, Chen-Xia, Huang, Yan-Feng, Liu, Jing, Zhang, Cheng-Da, Xie, Feng, Peng, Yi, Zhang, Yong, Li, Chun-Qi, Zhang, Li-Jiang
Published in Frontiers in cell and developmental biology (14.09.2021)
Published in Frontiers in cell and developmental biology (14.09.2021)
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Journal Article
Predicting the safety of medicines in pregnancy: A workshop report
Clements, J.M., Hawkes, R.G., Jones, D., Adjei, A., Chambers, T., Simon, L., Stemplewski, H., Berry, N., Price, S., Pirmohamed, M., Piersma, A.H., Waxenecker, G., Barrow, P., Beekhuijzen, M.E.W., Fowkes, A., Prior, H., Sewell, F.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.04.2020)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.04.2020)
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Journal Article
Developmental and reproductive toxicology studies in nonhuman primates
Chellman, Gary J., Bussiere, Jeanine L., Makori, Norbert, Martin, Pauline L., Ooshima, Yojiro, Weinbauer, Gerhard F.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.12.2009)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.12.2009)
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Journal Article
Variation and classification of chemically-induced zebrafish malformations for the ICH S5 (R3) guideline: an atlas for zebrafish teratogenesis
Mori, Kanako, Aoki, Yoshinobu, Hayashi, Mai, Sugimoto, Wataru, Ono, Mizuho, Umekita, Saaya, Niino, Tatsuhiro, Ebata, Tomonori, Mikashima, Fumito, Maki, Kazushige, Tanaka, Toshio, Hirata, Hiromi, Kojima, Hajime
Published in Journal of toxicological sciences (2025)
Published in Journal of toxicological sciences (2025)
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Journal Article