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Identifying Protein Quantitative Trait Loci in the Cerebrospinal Fluid Proteome
Reus, Lianne M., Teunissen, Charlotte E., Gobom, Johan, Vos, Stephanie J. B., Blennow, Kaj, Zetterberg, Henrik, Bertram, Lars, Visser, Pieter Jelle, Tijms, Betty M.
Published in ALZHEIMERS & DEMENTIA (01.06.2023)
Published in ALZHEIMERS & DEMENTIA (01.06.2023)
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Functional interpretation of genetic risk loci for dementia using a protein quantitative trait loci (pQTLs) approach in cerebrospinal fluid
Reus, Lianne M., Jansen, Iris E., Tijms, Betty M., Visser, Pieter Jelle, Lemstra, Afina W., Pijnenburg, Yolande A.L., van Der Flier, Wiesje, Teunissen, Charlotte E., Campo, Marta Del
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension
Harbaum, Lars, Rhodes, Christopher J., Wharton, John, Lawrie, Allan, Karnes, Jason H., Desai, Ankit A., Nichols, William C., Humbert, Marc, Montani, David, Girerd, Barbara, Sitbon, Olivier, Boehm, Mario, Novoyatleva, Tatyana, Schermuly, Ralph T., Ghofrani, H. Ardeschir, Toshner, Mark, Kiely, David G., Howard, Luke S., Swietlik, Emilia M., Gräf, Stefan, Pietzner, Maik, Morrell, Nicholas W., Wilkins, Martin R., Southgate, L, Machado, RD, Martin, J, Ouwehand, WH, Pauciulo, MW, Arora, A, Lutz, K, Ahmad, F, Archer, SL, Argula, R, Austin, ED, Badesch, D, Bakshi, S, Barnett, C, Benza, R, Bhatt, N, Burger, CD, Chakinala, M, Elwing, J, Fortin, T, Frantz, RP, Frost, A, Garcia, JGN, Harley, J, He, H, Hill, NS, Hirsch, R, Ivy, D, Klinger, J, Lahm, T, Marsolo, K, Martin, LJ, Nathan, SD, Oudiz, RJ, Rehman, Z, Robbins, I, Roden, DM, Rosenzweig, EB, Saydain, G, Schilz, R, Simms, RW, Simon, M, Tang, H, Tchourbanov, AY, Thenappan, T, Torres, F, Walsworth, AK, Walter, RE, White, RJ, Wilt, J, Yung, D, Kittles, R, Aman, J, Knight, J, Hanscombe, KB, Gall, H, Ulrich, A, Bogaard, HJ, Church, C, Coghlan, JG, Condliffe, R, Corris, PA, Danesino, C, Elliott, CG, Franke, A, Ghio, S, Gibbs, JSR, Houweling, AC, Kovacs, G, Laudes, M, MacKenzie Ross, RV, Moledina, S, Newnham, M, Olschewski, A, Olschewski, H, Peacock, AJ, Pepke-Zaba, J
Published in American journal of respiratory and critical care medicine (15.06.2022)
Published in American journal of respiratory and critical care medicine (15.06.2022)
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A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism
Cheng, Bolun, Yang, Xuena, Cheng, Shiqiang, Li, Chun’e, Zhang, Huijie, Liu, Li, Meng, Peilin, Jia, Yumeng, Wen, Yan, Zhang, Feng
Published in Molecular brain (23.07.2022)
Published in Molecular brain (23.07.2022)
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High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
Damoah, Christabel Esi, Snir, Omri, Hindberg, Kristian, Garred, Peter, Ludviksen, Judith K., Brækkan, Sigrid K., Morelli, Vânia M., Mollnes, Tom Eirik, Hansen, John-Bjarne
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2022)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2022)
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Journal Article
Clinically Relevant Circulating Protein Biomarkers for Type 1 Diabetes: Evidence From a Two-Sample Mendelian Randomization Study
Yazdanpanah, Nahid, Yazdanpanah, Mojgan, Wang, Ye, Forgetta, Vincenzo, Pollak, Michael, Polychronakos, Constantin, Richards, J. Brent, Manousaki, Despoina
Published in Diabetes care (01.01.2022)
Published in Diabetes care (01.01.2022)
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Mendelian randomization of circulating proteome identifies actionable targets in heart failure
Moncla, Louis-Hippolyte Minvielle, Mathieu, Samuel, Sylla, Mame Sokhna, Bossé, Yohan, Thériault, Sébastien, Arsenault, Benoit J., Mathieu, Patrick
Published in BMC genomics (13.08.2022)
Published in BMC genomics (13.08.2022)
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Deciphering proteins in Alzheimer’s disease: A new Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction
Yao, Minhao, Miller, Gary W., Vardarajan, Badri N., Baccarelli, Andrea A., Guo, Zijian, Liu, Zhonghua
Published in Cell genomics (11.12.2024)
Published in Cell genomics (11.12.2024)
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Genetically Determined Inflammation‐Related Proteins in Asthma and Type‐2 Signatures
Hernandez‐Pacheco, Natalia, Björkander, Sophia, Merid, Simon Kebede, Kere, Maura, Kumar, Ashish, Klevebro, Susanna, Mogensen, Ida, Ekström, Sandra, Janson, Christer, Palmberg, Lena, Hage, Marianne, Mälarstig, Anders, Merritt, Anne‐Sophie, Pershagen, Göran, Bergström, Anna, Kull, Inger, Schwenk, Jochen M., Melén, Erik
Published in Allergy (Copenhagen) (01.06.2025)
Published in Allergy (Copenhagen) (01.06.2025)
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Journal Article
Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome
Sasayama, Daimei, Hattori, Kotaro, Ogawa, Shintaro, Yokota, Yuuki, Matsumura, Ryo, Teraishi, Toshiya, Hori, Hiroaki, Ota, Miho, Yoshida, Sumiko, Kunugi, Hiroshi
Published in Human molecular genetics (01.01.2017)
Published in Human molecular genetics (01.01.2017)
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Journal Article
Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism
Skjeflo, Espen Waage, Brækkan, Sigrid Kufaas, Ludviksen, Judith Krey, Snir, Omri, Hindberg, Kristian, Mollnes, Tom Eirik, Hansen, John-Bjarne
Published in Blood (25.11.2021)
Published in Blood (25.11.2021)
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Journal Article
Proteomic insights into metabolic dysfunction-associated steatotic disease: Identifying therapeutic targets and assessing on-target side effects
Dai, Luojia, Liu, Zhenqiu, Guo, Chengnan, Fan, Hong, Zhang, Chengjun, Huang, Jiayi, Zhang, Xin, Zhao, Shuzhen, Wang, Haili, Zhang, Tiejun
Published in Life sciences (1973) (15.07.2025)
Published in Life sciences (1973) (15.07.2025)
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Journal Article
Association of TIM-1 (T-Cell Immunoglobulin and Mucin Domain 1) With Incidence of Stroke
Song, Lu, Sun, Jiangming, Söderholm, Martin, Melander, Olle, Orho-Melander, Marju, Nilsson, Jan, Borné, Yan, Engström, Gunnar
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2020)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2020)
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Journal Article
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders
Luo, Jie, Li, Ling, Niu, Mingming, Kong, Dehui, Jiang, Yi, Poudel, Suresh, Shieh, Annie W., Cheng, Lijun, Giase, Gina, Grennan, Kay, White, Kevin P., Chen, Chao, Wang, Sidney H., Pinto, Dalila, Wang, Yue, Liu, Chunyu, Peng, Junmin, Wang, Xusheng
Published in Molecular psychiatry (01.11.2024)
Published in Molecular psychiatry (01.11.2024)
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Journal Article
Plasma proteins and herpes simplex virus infection: a proteome-wide Mendelian randomization study
Fu, Canya, Xu, Wenjie, Xu, Xia, Zhao, Fei, Zheng, Canjie, Yin, Zhiying
Published in Virus genes (01.06.2025)
Published in Virus genes (01.06.2025)
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Journal Article
Genome-Wide Association Analysis of Blood Biomarkers in Chronic Obstructive Pulmonary Disease
Kim, Deog Kyeom, Cho, Michael H., Hersh, Craig P., Lomas, David A., Miller, Bruce E., Kong, Xiangyang, Bakke, Per, Gulsvik, Amund, Agustí, Alvar, Wouters, Emiel, Celli, Bartolome, Coxson, Harvey, Vestbo, Jørgen, MacNee, William, Yates, Julie C., Rennard, Stephen, Litonjua, Augusto, Qiu, Weiliang, Beaty, Terri H., Crapo, James D., Riley, John H., Tal-Singer, Ruth, Silverman, Edwin K.
Published in American journal of respiratory and critical care medicine (15.12.2012)
Published in American journal of respiratory and critical care medicine (15.12.2012)
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Journal Article
The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway
Tran, Paul MH, Purohit, Sharad, Kim, Eileen, bin Satter, Khaled, Hopkins, Diane, Waugh, Kathleen, Dong, Fran, Onengut-Gumuscu, Suna, Rich, Stephen S., Rewers, Marian, She, Jin-Xiong
Published in Journal of translational autoimmunity (Online) (01.01.2021)
Published in Journal of translational autoimmunity (Online) (01.01.2021)
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Journal Article
Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes
Tran, Paul M. H., Dong, Fran, Bin Satter, Khaled, Richardson, Katherine P., Patel, Roshni, Tran, Lynn K. H., Hopkins, Diane, Kolhe, Ravindra, Waugh, Kathleen, Rewers, Marian, Purohit, Sharad
Published in Endocrines (01.09.2022)
Published in Endocrines (01.09.2022)
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Journal Article
Evaluating the associations between intelligence quotient and multi-tissue proteome from the brain, CSF and plasma
Shi, Sirong, Chen, Yujing, Chu, Xiaoge, Shi, Panxing, Wang, Bingyi, Cai, Qingqing, He, Dan, Zhang, Na, Qin, Xiaoyue, Wei, Wenming, Zhao, Yijing, Jia, Yumeng, Zhang, Feng, Wen, Yan
Published in Brain communications (2024)
Published in Brain communications (2024)
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Journal Article
Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator
Carayol, Jérôme, Chabert, Christian, Di Cara, Alessandro, Armenise, Claudia, Lefebvre, Gregory, Langin, Dominique, Viguerie, Nathalie, Metairon, Sylviane, Saris, Wim H. M., Astrup, Arne, Descombes, Patrick, Valsesia, Armand, Hager, Jörg
Published in Nature communications (12.12.2017)
Published in Nature communications (12.12.2017)
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