Therapeutic and diagnostic nanomaterials

This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions. Ecofriendly methods which are ideal for the synthesis of medicinally valued nanoparticles are explained and the characteristic features of these particles projected. The role of these...

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Bibliographic Details
Main Author Devasena, T. (Author)
Format Electronic eBook
LanguageEnglish
Published Singapore : Springer, [2016]
SeriesSpringerBriefs in applied sciences and technology. Nanotheranostics.
Subjects
Biomedical materials.
elektronické knihy
electronic books
Online AccessPlný text

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100 1 |a Devasena, T.,  |e author. 
245 1 0 |a Therapeutic and diagnostic nanomaterials /  |c Devasena T. 
264 1 |a Singapore :  |b Springer,  |c [2016] 
264 4 |c ©2017 
300 |a 1 online resource (vii, 109 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a SpringerBriefs in applied sciences and technology, Nanotheranostics,  |x 2191-530X 
504 |a Includes bibliographical references. 
505 0 |a Introduction; 1 Diagnostic and Therapeutic Nanomaterials; 1.1 Why Are Nanoparticles Ideal Diagnostic and Therapeutic Agents?; 1.2 Nanotheranostic Candidates; 1.3 Safety Concerns with Medically Important Nanoparticles; References; 2 Multifunctional Nanoparticles; 2.1 Stabilizing Ligands; 2.1.1 Biomolecules; 2.1.2 Avidin-Biotin Conjugate; 2.2 Targeting Ligands; 2.2.1 Antibodies; 2.2.2 Antibody Fragments/Antibody Derivatives; 2.2.3 Peptides; 2.2.4 Aptamers; 2.2.5 Small Targeting Molecules; 2.3 Imaging Ligands; 2.4 Biocompatibility Ligands; 2.5 Anti-immunogenic Ligands; References. 
505 8 |a 3 Biomarkers3.1 Biochemical Markers; 3.1.1 Cardiac Markers; 3.1.2 Cytokines; 3.1.3 Cancer Markers; 3.1.4 Cell Adhesion Molecules (CAMs); 3.1.5 Enzymes; 3.1.6 Hematological Biomarkers; 3.1.7 Oxidative Stress Markers; 3.2 Genetic Markers; 3.2.1 Single Locus Markers; 3.2.2 Multiple Loci Markers; 3.2.3 Examples of Genetic Markers; 3.3 Histopathological Markers; References; 4 Diagnostic and Therapeutic Techniques; 4.1 Diagnostic Techniques Using Nanoparticles; 4.2 Therapeutic Techniques Using Nanoparticles; References; 5 Nanotoxicity and Risk Assessment; 5.1 CNT Toxicity. 
505 8 |a 5.2 Silica and Titania Nanoparticles5.3 Fullerene; 5.4 Quantum Dots; 5.5 Manganese Nanoparticles; References; 6 Applications of Select Nanomaterials; 6.1 Dendrimers; 6.1.1 Dendrimers in Therapeutic Applications; 6.1.2 Nanoscale Containers; 6.1.3 Dendrimers in Gene Transfection; 6.1.4 Dendrimers in Diagnostic Applications; 6.2 Antibodies; 6.2.1 Blood-Brain Barrier; 6.2.2 Nanoimmunosensors; 6.2.3 Types of Immunosensors; 6.2.4 Preparation of HDL-like Nanoparticles; 6.2.5 Plaques in an ApoE-/- Model; 6.2.6 Gold Nanoparticles. 
505 8 |a 6.2.6.1 Applications of Gold Nanoparticles with Enhanced Raman Spectroscopy6.3 Lipid-Based Nanocarriers; 6.3.1 Liposomes; 6.3.1.1 Stealth Liposomes: The Second-Generation Liposomes; 6.3.1.2 Applications of Nanoliposomes; Liposomal Anticancer Agents; Liposomal Anti-infective Drugs; Vaccine Delivery; Diagnostic Applications of Liposomes; 6.3.1.3 Solid-Lipid Nanoparticles; Applications of SLNs; 6.3.1.4 Cubosomes; Cubosomes for Ocular Inflammation; 6.4 Viral Nanoparticles; 6.4.1 Pharmacokinetics; 6.4.2 Disadvantages: Nonspecific Interaction and Immunogenicity; 6.4.3 Applications. 
505 8 |a 6.4.3.1 VNPs as Imaging Probes and Drug Carriers for Vascular Endothelial Cells6.4.3.2 CPMVs as Carriers for Delivering Cargo into the Central Nervous System; 6.5 Nanomaterial-Based Biomedical Devices; 6.5.1 Micropumps; 6.5.1.1 Components of Micropumps; 6.5.1.2 Applications and Advantages of a Silicon-Based HPMP; 6.5.2 Microneedles; 6.5.2.1 Applications of Microneedles; 6.5.3 Implantable Microchip Devices for Drug Delivery; 6.5.4 Nanorobots; 6.5.4.1 Tools or Components of Nanorobots; 6.5.4.2 Nanorobot Locomotion; 6.5.4.3 Power for the Navigation of Nanorobots; 6.5.4.4 Tracking of Nanorobots. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions. Ecofriendly methods which are ideal for the synthesis of medicinally valued nanoparticles are explained and the characteristic features of these particles projected. The role of these particles in the therapeutic field, and the induced biological changes in some diseases are discussed. The main focus is on inflammation, oxidative stress and cellular membrane integrity alterations. The effect of nanoparticles on these changes produced by various agents are highlighted using in vitro and in vivo models. The mechanism of nanoparticles in ameliorating the biological changes is supported by relevant images and data. Finally, the brief demonstrates recent developments on the use of nanoparticles in diagnosis or sensing of some biological materials and biologically hazardous environmental materials. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Biomedical materials. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
776 0 8 |i Erscheint auch als:  |n Druck-Ausgabe  |t T., Devasena. Therapeutic and Diagnostic Nanomaterials 
830 0 |a SpringerBriefs in applied sciences and technology.  |p Nanotheranostics. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-981-10-0923-5  |y Plný text 
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