11th International Conference on Practical Applications of Computational Biology & Bioinformatics

• Corporate Author: International Conference on Practical Applications of Computational Biology & Bioinformatics Porto, Portugal
• Other Authors: Fdez.-Riverola, Florentino (Editor), Mohd Saberi Mohamad (Editor), Rocha, Miguel P. (Editor), Paz Santana, Juan F. de (Editor), Pinto, Tiago (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham, Switzerland : Springer, [2017]
• Series: Advances in intelligent systems and computing ; 616.
• Subjects: Computational biology > Congresses.; Bioinformatics > Congresses.; elektronické knihy; electronic books

Biological and biomedical research are increasingly driven by experimental techniques that challenge our ability to analyse, process and extract meaningful knowledge from the underlying data. The impressive capabilities of next-generation sequencing technologies, together with novel and constantly e...

Table of Contents:

• Preface; Organization; General Co-chairs; Program Committee; Organising Committee; PACBB 2016 Sponsors; Contents; S2P: A Desktop Application for Fast and Easy Processing of 2D-Gel and MALDI-Based Mass Spectrometry ... ; Abstract; 1 Introduction; 2 Materials and Methods; 2.1 Case Study; 2.2 Implementation; 3 Results and Discussion; 4 Conclusions; Acknowledgements; References; Multi-Enzyme Pathway Optimisation Through Star-Shaped Reachable Sets; 1 Introduction; 1.1 Multi-Enzyme Pathways; 1.2 Mathematical Setup; 1.3 Optimal Control; 2 Star-Shaped Reachable Sets.
• 2.1 Reachable Sets and Optimization2.2 Star-Shaped Sets Generated by Multi-Enzyme Pathway; 2.3 Examples; 3 Conclusions; References; Automated Collection and Sharing of Adaptive Amino Acid Changes Data; Abstract; 1 Introduction; 2 ADOPS Batch Mode; 3 B+ Database Implementation; 4 Conclusion; Acknowledgements; References; ROC632: An Overview; 1 Introduction; 1.1 ROC Curves; 1.2 Area Under the ROC Curve; 1.3 The Bootstrap Method; 2 Materials and Methods; 3 Results and Discussion; 3.1 Evaluation of the boot. ROC Function; 3.2 Assessment of the boot. ROCt Function; 4 Conclusions; References.
• Processing 2D Gel Electrophoresis Images for Efficient Gaussian Mixture ModelingAbstract; 1 Introduction; 2 Materials and Methods; 2.1 Data; 2.2 Processing Methods; 2.3 Gaussian Mixture Modeling; 3 Results and Discussion; 3.1 Spot Detection Performance; 3.2 Goodness of Model Fit; 4 Conclusions; Acknowledgments; References; Improving Document Prioritization for Protein-Protein Interaction Extraction Using Shallow Linguistics and Word Embeddings; 1 Introduction; 2 Methods; 2.1 Data; 2.2 Feature Extraction; 2.3 Document Classification; 3 Results; 4 Conclusions; References.
• K-Means Clustering with Infinite Feature Selection for Classification Tasks in Gene Expression DataAbstract; 1 Introduction; 2 Materials and Methods; 2.1 Datasets and Tools; 2.2 Centroid Clustering Analysis (CCA-I); 2.3 Clustering Validation (CV-II); 2.4 Feature Selection (FS-III); 2.5 Classification (C-IV); 3 Results and Discussion; 3.1 Accuracy and Number of the Selected Genes in the Subset; 3.2 List of the Selected Genes; 4 Conclusion; Acknowledgements; References; Classification of Colorectal Cancer Using Clustering and Feature Selection Approaches; Abstract; 1 Introduction.
• 2 Material and Methods2.1 Dataset and Tools; 2.2 Clustering; 2.3 Clustering Validation; 2.4 Feature Selection; 2.5 Classification; 3 Results and Discussion; 4 Conclusion; Acknowledgements; References; Development of Text Mining Tools for Information Retrieval from Patents; 1 Introduction; 2 Patent Pipeline Development; 3 Results; 4 Conclusions; References; How Can Photo Sharing Inspire Sharing Genomes?; 1 Introduction; 2 An Analogy Between Sharing Photos and Sharing Genomes; 2.1 Some Portions of Data Are More Privacy-Sensitive Than Others; 2.2 One's Data May Affect the Privacy of Others.